1326242-72-1Relevant articles and documents
Development of Scalable Routes to 1-Bicyclo[1.1.1]pentylpyrazoles
Zarate, Cayetana,Ardolino, Michael,Morriello, Gregori J.,Logan, Kaitlyn M.,Kaplan, William P.,Torres, Luis,Li, Derun,Chen, Meng,Li, Hongming,Su, Jing,Fuller, Peter,Maddess, Matthew L.,Song, Zhiguo Jake
, p. 642 - 647 (2021)
The application of bicyclo[1.1.1]pentanes (BCPs) as phenyl bioisosteres has garnered significant attention, as these structural motifs can improve the physiochemical profiles of drug candidates. Despite the potential of using 1-bicyclo[1.1.1]pentylpyrazol
PYRIMIDINE AND TRIAZINE DERIVATIVES AND THEIR USE AS AXL INHIBITORS
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Page/Page column 99, (2016/07/05)
Compounds of the general formula(I): (I) processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.
SUBSTITUTED ACETYL-COA CARBOXYLASE INHIBITORS
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Page/Page column 19, (2012/11/07)
The invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; wherein G is R1, R2 and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase enzyme(s) in an animal.