132836-42-1 Usage
General Description
YS 49 is a chemical compound known for its role in medical research, particularly in the field of cardiology. It acts as a PI3K/Akt (Phosphoinositide 3-kinases/ Protein kinase B) and MEK/ERK (Mitogen-activated protein kinase kinase/ Extracellular signal-regulated kinases) activator. These pathways have been identified as key components in various cellular processes including cell growth and heart protection. YS 49 has been shown to have protective effects against myocardial ischemia/reperfusion (I/R) injuries in animal models and cardiomyocytes. However, the safety and efficacy of this compound for therapeutic application in humans is still being studied and assessed.
Check Digit Verification of cas no
The CAS Registry Mumber 132836-42-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,8,3 and 6 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 132836-42:
(8*1)+(7*3)+(6*2)+(5*8)+(4*3)+(3*6)+(2*4)+(1*2)=121
121 % 10 = 1
So 132836-42-1 is a valid CAS Registry Number.
132836-42-1Relevant articles and documents
Biocatalytic production of tetrahydroisoquinolines
Ruff, Bettina M.,Br?se,O'Connor, Sarah E.
, p. 1071 - 1074 (2012/03/27)
The promiscuity of the enzyme norcoclaurine synthase is described. This biocatalyst yielded a diverse array of substituted tetrahydroisoquinolines by cyclizing dopamine with various acetaldehydes in a Pictet-Spengler reaction. This enzymatic reaction may provide a biocatalytic route to a range of tetrahydroisoquinoline alkaloids.
