1330667-68-9

Basic information

• Product Name: 2-(3,4-dichlorophenylamino)-5-(2R,3R-O-isopropylidene-4R-O-allyl-tetrahydrofuro-2,3,4-triol-5S)-1,3,4-thiadiazole
• Synonyms: 2-(3,4-dichlorophenylamino)-5-(2R,3R-O-isopropylidene-4R-O-allyl-tetrahydrofuro-2,3,4-triol-5S)-1,3,4-thiadiazole
• CAS NO: 1330667-68-9
• Molecular Weight: 444.339
• Mol File: 1330667-68-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3,4-dichlorophenylamino)-5-(2R,3R-O-isopropylidene-4R-O-allyl-tetrahydrofuro-2,3,4-triol-5S)-1,3,4-thiadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-dichlorophenylamino)-5-(2R,3R-O-isopropylidene-4R-O-allyl-tetrahydrofuro-2,3,4-triol-5S)-1,3,4-thiadiazole(1330667-68-9)
• EPA Substance Registry System: 2-(3,4-dichlorophenylamino)-5-(2R,3R-O-isopropylidene-4R-O-allyl-tetrahydrofuro-2,3,4-triol-5S)-1,3,4-thiadiazole(1330667-68-9)

Safety Data

• Hazardous Substances Data: 1330667-68-9(Hazardous Substances Data)

Upstream product

• 38901-32-5 N-(3,4-dichlorophenyl)hydrazinecarbothioamide 
• 152185-56-3 3-O-Allyl-1,2-O-isopropylidene-α-D-xylo-pentodialdose 
• 1628180-85-7 C₁₈H₂₁Cl₂N₃O₄S 

Relevant articles and documents

Design, synthesis and bioactivity of novel glycosylthiadiazole derivatives

A series of novel glycosylthiadiazole derivatives, namely 2-phenylamino-5- glycosyl-1,3,4-thiadiazoles, were designed and synthesized by condensation between sugar aldehydes A/B and substituted thiosemicarbazide C followed by oxidative cyclization by treating with manganese dioxide. The original fungicidal activities results showed that some title compounds exhibited excellent fungicidal activities against Sclerotinia sclerotiorum (Lib.) de Bary and Pyricularia oryzae Cav, especially compounds F-5 and G-8 which displayed better fungicidal activities than the commercial fungicide chlorothalonil. At the same time, the preliminary studies based on the Elson-Morgan method indicated that many compounds exhibited some inhibitory activity toward glucosamine-6- phosphate synthase (GlmS). The structure-activity relationships (SAR) are discussed in terms of the effects of the substituents on both the benzene and the sugar ring.