133118-47-5

Basic information

• Product Name: 2-<2-(3,5-difluorophenyl)-4-imidazolyl>ethanamine
• Synonyms: 2-<2-(3,5-difluorophenyl)-4-imidazolyl>ethanamine
• CAS NO: 133118-47-5
• Molecular Weight: 223.225
• Mol File: 133118-47-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-<2-(3,5-difluorophenyl)-4-imidazolyl>ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-<2-(3,5-difluorophenyl)-4-imidazolyl>ethanamine(133118-47-5)
• EPA Substance Registry System: 2-<2-(3,5-difluorophenyl)-4-imidazolyl>ethanamine(133118-47-5)

Safety Data

• Hazardous Substances Data: 133118-47-5(Hazardous Substances Data)

Upstream product

• 1003034-18-1 N-tert-butylcarbonyl-2-iodohidtamine 
• 156545-07-2 3,5-difluorophenylboronic acid 
• 65465-66-9 2-Oxo-4-phthalimido-1-butyl acetate 

Relevant articles and documents

Synthesis of substituted 2-phenylhistamines via a microwave promoted Suzuki coupling

Substitutions on the 2-position of the imidazole ring of histamine have proven useful in a number of biochemical settings. Current art for the synthesis of these constructs relies upon a cumbersome and low-yielding condensation reaction. Here-in we report a new procedure for the synthesis of a series of substituted 2-phenylhistamines utilizing a microwave-promoted Suzuki coupling.