1332332-38-3

Basic information

• Product Name: 5-{[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl}-4-[4-(6-hydroxy-2-naphthalenyl)phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one
• Synonyms: 5-{[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl}-4-[4-(6-hydroxy-2-naphthalenyl)phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one
• CAS NO: 1332332-38-3
• Molecular Weight: 454.528
• Mol File: 1332332-38-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-{[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl}-4-[4-(6-hydroxy-2-naphthalenyl)phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-{[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl}-4-[4-(6-hydroxy-2-naphthalenyl)phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one(1332332-38-3)
• EPA Substance Registry System: 5-{[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl}-4-[4-(6-hydroxy-2-naphthalenyl)phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one(1332332-38-3)

Safety Data

• Hazardous Substances Data: 1332332-38-3(Hazardous Substances Data)

Upstream product

• 1332333-19-3 N-(4-bromophenyl)-2-{[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]acetyl}hydrazinecarboxamide 
• 1332333-18-2 2-[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]acetohydrazide 
• 1332333-17-1 ethyl[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]acetate 
• 204688-61-9 2‐[(3S)‐1‐[(tert‐butoxy)carbonyl]pyrrolidin‐3‐yl]acetic acid 
• 173194-95-1 (6-hydroxynaphthalen-2-yl)boronic acid 
• 1332333-20-6 4-(4-bromophenyl)-5-{[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl}-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 2493-02-9 4-bromophenyl isocyanate 

Relevant articles and documents

TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS

This invention relates to the use of triazolone derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of triazolones in the treatment of cancer.