1332357-14-8 Usage
Description
5, 5'-[(2R, 5R)-1-[3,5-difluoro-4-(4-(4-fluorophenyl)1-piperidinyl)phenyl]-2,5-pyrrolidinediyl]bis[6-fluoro-2-(2S)-2-pyrrolidinyl 1H-benzimidzole] is a complex organic compound with antiviral properties. It is an intermediate in the synthesis of Pibrentasvir (1353900-92-1), a medication used to treat chronic hepatitis C virus infection.
Uses
Used in Pharmaceutical Industry:
5, 5'-[(2R, 5R)-1-[3,5-difluoro-4-(4-(4-fluorophenyl)1-piperidinyl)phenyl]-2,5-pyrrolidinediyl]bis[6-fluoro-2-(2S)-2-pyrrolidinyl 1H-benzimidzole] is used as an antiviral agent for the treatment of chronic hepatitis C virus infection. It serves as an intermediate in the synthesis of Pibrentasvir, which is a direct-acting antiviral drug that inhibits the replication of the hepatitis C virus, leading to viral clearance and improved patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 1332357-14-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,3,2,3,5 and 7 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1332357-14:
(9*1)+(8*3)+(7*3)+(6*2)+(5*3)+(4*5)+(3*7)+(2*1)+(1*4)=128
128 % 10 = 8
So 1332357-14-8 is a valid CAS Registry Number.
1332357-14-8Relevant articles and documents
PROCESS FOR MANUFACTURING PIBRENTASVIR ACTIVE DRUG SUBSTANCE
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Paragraph 0119, (2020/03/23)
The present invention relates to compositions of pibrentasvir, drug products thereof, and processes and intermediates for the preparation thereof. This invention relates to the drug product, active drug substance, intermediates, and processes of pibrentasvir, a NS5A inhibitor that is useful in the treatment of hepatitis C.
