1332889-22-1

Basic information

• Product Name: Foretinib H2O
• Synonyms: Foretinib H2O
• CAS NO: 1332889-22-1
• Molecular Formula: C34H36F2N4O7
• Mol File: 1332889-22-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Foretinib H2O(CAS DataBase Reference)
• NIST Chemistry Reference: Foretinib H2O(1332889-22-1)
• EPA Substance Registry System: Foretinib H2O(1332889-22-1)

Safety Data

• Hazardous Substances Data: 1332889-22-1(Hazardous Substances Data)

Usage

Description

Foretinib H2O, also known as XL880 (GSK1363089, EXEL-2880), is an ATP-competitive inhibitor of MET and KDR with IC50 values of 0.4 nM and 0.9 nM, respectively. It is a pharmaceutical compound designed to target specific protein receptors involved in cell signaling pathways, making it a promising candidate for various therapeutic applications.

Uses

Used in Pharmaceutical Industry:
Foretinib H2O is used as an inhibitor for [application type] in the pharmaceutical industry for [application reason] targeting the MET and KDR receptors, which play a role in cell signaling pathways. Its high specificity and potency make it a valuable compound for the development of targeted therapies.
Used in Cancer Treatment:
Foretinib H2O is used as an anticancer agent for inhibiting the MET and KDR receptors, which are often overexpressed in various types of cancer. By targeting these receptors, Foretinib H2O may help to slow down tumor growth and progression, potentially improving patient outcomes.
Used in Research and Development:
Foretinib H2O is used as a research tool for studying the role of MET and KDR receptors in cell signaling and their involvement in various diseases, including cancer. Its use in research may lead to a better understanding of these pathways and the development of new therapeutic strategies.