133858-35-2Relevant articles and documents
Concerning the nucleophilic displacement of a methylsulfanyl group on substituted pyrimidinones
Kikelj, Vincent,Grosjean, Sylvain,Meslin, Jean-Claude,Julienne, Karine,Deniaud, David
experimental part, p. 2811 - 2815 (2010/10/19)
The nucleophilic displacement of a methylsulfanyl group (SMe) at the C2-position on a pyrimidin-4-one scaffold was achieved after oxidation into a methylsulfonyl group (SO2Me) using dimethyldioxirane (DMDO), a powerful electrophilic oxygen atom transfer agent. The introduction of amino groups as well as formation of carbon-carbon bonds was thus demonstrated. Georg Thieme Verlag Stuttgart.