134111-35-6

Basic information

• Product Name: 4-THIOTHYMIDINE
• Synonyms: 4-THIOTHYMIDINE;Aids104084;Aids-104084;1-(2-Deoxy-4-thio-alpha-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
• CAS NO: 134111-35-6
• Molecular Formula: C₁₀H₁₄N₂O₄S
• Molecular Weight: 258.29
• Mol File: 134111-35-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Water (Slightly, Sonicated)
• CAS DataBase Reference: 4-THIOTHYMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-THIOTHYMIDINE(134111-35-6)
• EPA Substance Registry System: 4-THIOTHYMIDINE(134111-35-6)

Safety Data

• Hazardous Substances Data: 134111-35-6(Hazardous Substances Data)

Upstream product

• 65-71-4 thymin 
• 169736-17-8 1-O-acetyl-2-deoxy-4-thio-3,5-di-O-p-toluoyl-4-thio-D-erythro-pentofuranose 
• 7288-28-0 2,4-bis(trimethylsiloxy)-5-methylpyrimidine 
• 134938-97-9 benzyl 3,5-di-O-benzyl-2-deoxy-1,4-dithio-D-erythro-pentofuranoside 
• 134700-17-7 α-3',5'-di-O-benzyl-4'-thiothymidine 
• 134111-38-9 1-(2-deoxy-4-thio-3,5-di-O-toluoyl-α-D-erythro-pentofuranosyl)thymine 

Downstream Products

• 65-71-4 thymin 

Relevant articles and documents

MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF

The present disclosure provides oligomeric compounds comprising a modified oligonucleotide having at least one stereo-non-standard 4' -thio nucleoside.

The synthesis and antiviral activity of some 4'-thio-2'-deoxy nucleoside analogues

Starting from benzyl 3,5-di-O-benzyl-2-deoxy-1,4-dithio-D-erythro-pentofuranoside (4), the following 2'-deoxy nucleoside analogues have been synthesized: 4'-thiothymidine (8), 3'-azido-4'-thio-deoxythymidine (10), and (E)-5-(2-bromovinyl)-4'-thio-2'-deoxy