1341205-77-3

Basic information

• Product Name: 3-(2-phenylpropan-2-yl)-6-(4-trifluoromethoxyphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
• CAS NO: 1341205-77-3
• Molecular Weight: 404.416
• Mol File: 1341205-77-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-phenylpropan-2-yl)-6-(4-trifluoromethoxyphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-phenylpropan-2-yl)-6-(4-trifluoromethoxyphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(1341205-77-3)
• EPA Substance Registry System: 3-(2-phenylpropan-2-yl)-6-(4-trifluoromethoxyphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(1341205-77-3)

Safety Data

• Hazardous Substances Data: 1341205-77-3(Hazardous Substances Data)

Upstream product

• 1038320-22-7 4-amino-5-(2-phenylpropan-2-yl)-4H-[1,2,4]-triazole-3-thiol 
• 330-12-1 4-trifluoromethoxybenzoic acid 
• 57625-74-8 methyl 2-methyl-2-phenylpropionate 
• 5809-15-4 2-methyl-2-phenyl propanoyl hydrazide 

Relevant articles and documents

Synthesis and biological activities of a novel series of 3,6-disubstituted-1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazoles containing gem-dimethylbenzyl moiety

A novel series of 3,6-disubstituted-1,2,4-triazolo-[3,4-b]-1,3,4- thiadiazoles (6a-r) containing gem-dimethyl benzyl moiety were prepared by the condensation of 4-amino-3-aryl/aralkyl substituted-5-mercapto-1,2,4-triazoles (5a-c) with various fluoro substituted aromatic acids in the presence of POCl3. IR, 1H NMR, 13C NMR, 2D NMR (COSY), and mass spectral data confirmed the structures of all the synthesized compounds. All the compounds were also screened for their antibacterial, antifungal and analgesic activities. Compounds 6b, 6d, 6f, 6g, 6h, 6i, 6m, 6n, 6o, 6p, and 6r exhibited promising antibacterial and compounds 6a, 6d, 6f, 6g, 6h, 6k, 6m, 6o, 6p, and 6q showed significant analgesic activities.