1343480-61-4Relevant articles and documents
Novel 1-alkynyl substituted 1,2-dihydroquinoline derivatives from nimesulide (and their 2-oxo analogues): A new strategy to identify inhibitors of PDE4B
Pal, Sarbani,Durgadas, Shylaprasad,Nallapati, Suresh Babu,Mukkanti, Khagga,Kapavarapu, Ravikumar,Meda, Chandana Lakshmi T.,Meda, Kishore V.L.,Pal, Manojit
, p. 6573 - 6576 (2011/12/04)
A number of novel 1-(3-arylprop-2-ynyl) substituted 1,2-dihydroquinoline derivatives related to nimesulide and their 2-oxo analogues have been designed as potential inhibitors of PDE4. All these compounds were synthesized by using Sonogashira coupling as