1346604-19-0

Basic information

• Product Name: rac Diacetolol-d7
• Synonyms: rac Diacetolol-d7;(±)-Diacetolol-d7;(±)-N-[3-Acetyl-4-[2-hydroxy-3-[(1-Methylethyl-d7)aMino]propoxy]phenyl]acetaMide;1-(4-AcetaM;Acetylacebutolol-d7;Diacetolol-d7;DL-3'-Acetyl-4'-[2-hydroxy-3-[(isopropyl-d7)aMino]propoxy]acetanilide;M and B 16942-d7
• CAS NO: 1346604-19-0
• Molecular Formula: C16H24N2O4
• Molecular Weight: 308.37276
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Metabolites & Impurities;Pharmaceuticals
• Mol File: 1346604-19-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: rac Diacetolol-d7(CAS DataBase Reference)
• NIST Chemistry Reference: rac Diacetolol-d7(1346604-19-0)
• EPA Substance Registry System: rac Diacetolol-d7(1346604-19-0)

Safety Data

• Hazardous Substances Data: 1346604-19-0(Hazardous Substances Data)

Usage

Description

rac Diacetolol-d7, also known as A123800, is a labeled principal metabolite of Acebutolol. It possesses less β-adrenoceptor blocking potency but exhibits greater cardioselectivity, particularly in atrial relative to tracheal tissue. This characteristic makes it a valuable compound for various applications in the pharmaceutical and medical industries.

Uses

Used in Pharmaceutical Industry:
rac Diacetololol-d7 is used as a metabolite for the development of drugs with improved cardioselectivity. Its application reason is due to its lower β-adrenoceptor blocking potency and higher cardioselectivity, which can lead to more targeted and effective treatments for specific cardiac conditions.
Used in Medical Research:
In the field of medical research, rac Diacetolol-d7 is used as a research tool for studying the effects of β-adrenoceptor blocking agents on atrial and tracheal tissues. Its application reason is to gain a better understanding of the mechanisms and selectivity of these agents, which can contribute to the development of more effective and safer medications for heart-related conditions.
Used in Drug Development:
rac Diacetolol-d7 is utilized as a compound in the development of new drugs with enhanced cardioselectivity and reduced side effects. Its application reason is the potential to create medications that are more effective in treating specific cardiac conditions while minimizing the impact on other tissues, such as the tracheal tissue.