134931-01-4Relevant articles and documents
Erythromycylamine.
Massey,Kitchell,Martin,Gerzon,Murphy
, p. 157 - 160 (2007/10/11)
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134931-01-4
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Basic information
- Product Name: (9Z)-ErythroMycin A OxiMe
- Synonyms: (9Z)-ErythroMycin A OxiMe;(3R,4S,5S,6R,7R,9R,10Z,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one
- CAS NO:134931-01-4
- Molecular Formula: C37H68N2O13
- Molecular Weight: 748.94142
- EINECS: N/A
- Product Categories: Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
- Mol File: 134931-01-4.mol
- Article Data: 1
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 841.0±65.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.28±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: Dichloromethane, Ethyl Acetate
- PKA: 11.96±0.70(Predicted)
- CAS DataBase Reference: (9Z)-ErythroMycin A OxiMe(CAS DataBase Reference)
- NIST Chemistry Reference: (9Z)-ErythroMycin A OxiMe(134931-01-4)
- EPA Substance Registry System: (9Z)-ErythroMycin A OxiMe(134931-01-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 134931-01-4(Hazardous Substances Data)
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134931-01-4 Usage
Description
(9Z)-ErythroMycin A OxiMe, also known as (9Z)-Erythromycin A Oxime, is a metabolite of Roxithromycin (R700850) found in humans. It is characterized by its light yellow powder form and is derived from the Erythromycin group of macrolide antibiotics. (9Z)-ErythroMycin A OxiMe exhibits unique chemical properties and has potential applications in various industries due to its distinctive characteristics.Uses
Used in Pharmaceutical Industry:(9Z)-ErythroMycin A OxiMe is used as an intermediate compound for the synthesis of semi-synthetic macrolide antibiotics. Its role in the pharmaceutical industry is crucial, as it contributes to the development of new antibiotics with improved properties, such as enhanced efficacy, reduced side effects, and increased resistance to bacterial resistance mechanisms.
Used in Research and Development:
In the field of research and development, (9Z)-ErythroMycin A OxiMe serves as a valuable tool for studying the structure-activity relationships of macrolide antibiotics. This knowledge can be applied to design and develop novel macrolide-based drugs with improved pharmacological profiles and targeted applications.
Used in Drug Metabolism Studies:
(9Z)-ErythroMycin A OxiMe is also utilized in drug metabolism studies to understand the metabolic pathways and pharmacokinetics of macrolide antibiotics in humans. This information is essential for optimizing drug dosages, minimizing side effects, and ensuring the safe and effective use of these medications.
Used in Quality Control and Standardization:
The light yellow powder form of (9Z)-ErythroMycin A OxiMe makes it suitable for use in quality control and standardization processes in the pharmaceutical industry. It can be employed as a reference material to ensure the consistency, purity, and potency of macrolide antibiotic products.
Check Digit Verification of cas no
The CAS Registry Mumber 134931-01-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,9,3 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.Calculate Digit Verification of CAS Registry Number 134931-01:
(8*1)+(7*3)+(6*4)+(5*9)+(4*3)+(3*1)+(2*0)+(1*1)=114
114 % 10 = 4
So 134931-01-4 is a valid CAS Registry Number.
134931-01-4Upstream product
134931-01-4Downstream Products
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(9Z)-ErythroMycin A OxiMe
