1349837-48-4

Basic information

• Product Name: JWH 081 8-methoxynaphthyl isomer
• Synonyms: JWH 081 8-methoxynaphthyl isomer;(8-methoxynaphthalen-1-yl)-(1-pentylindol-3-yl)methanone
• CAS NO: 1349837-48-4
• Molecular Formula: C25H25NO2
• Molecular Weight: 371.4715
• Mol File: 1349837-48-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 562.8±25.0 °C(Predicted)
• Appearance: /
• Density: 1.11±0.1 g/cm3(Predicted)
• CAS DataBase Reference: JWH 081 8-methoxynaphthyl isomer(CAS DataBase Reference)
• NIST Chemistry Reference: JWH 081 8-methoxynaphthyl isomer(1349837-48-4)
• EPA Substance Registry System: JWH 081 8-methoxynaphthyl isomer(1349837-48-4)

Safety Data

• Hazardous Substances Data: 1349837-48-4(Hazardous Substances Data)

Usage

Description

JWH 081 8-methoxynaphthyl isomer is a synthetic cannabinoid that exhibits high affinity for the central CB1 receptor and a ten-fold reduced affinity for the peripheral CB2 receptor. It is structurally distinct from JWH 081 due to the methoxy group being attached to the naphthyl rings at the 8 position, rather than the 4 position. The biological and toxicological properties of this compound have not been fully characterized, and it is intended for forensic and research purposes.

Uses

Used in Forensic Applications:
JWH 081 8-methoxynaphthyl isomer is used as a forensic tool for the detection and identification of synthetic cannabinoids in various samples, such as blood, urine, and hair. Its unique structural properties allow for accurate differentiation from other cannabinoids, aiding in the investigation of drug-related cases.
Used in Research Applications:
JWH 081 8-methoxynaphthyl isomer is used as a research compound to study the interactions between synthetic cannabinoids and the CB1 and CB2 receptors. This helps researchers understand the mechanisms of action, potential therapeutic applications, and possible side effects of these compounds, ultimately contributing to the development of safer and more effective cannabinoid-based treatments.
Used in Drug Development:
JWH 081 8-methoxynaphthyl isomer is used as a starting point for the development of new drugs targeting the CB1 and CB2 receptors. By studying its structural properties and interactions with these receptors, researchers can design and synthesize novel compounds with improved pharmacological profiles, potentially leading to the creation of more effective medications for various conditions.
Used in Toxicological Studies:
JWH 081 8-methoxynaphthyl isomer is used as a test compound in toxicological research to evaluate the safety and potential side effects of synthetic cannabinoids. This helps in understanding the risks associated with their use and informs the development of guidelines and regulations for their administration and consumption.
Used in Analytical Chemistry:
JWH 081 8-methoxynaphthyl isomer is used as a reference material in the development and validation of analytical methods for the detection and quantification of synthetic cannabinoids in various matrices. This ensures the accuracy and reliability of test results, which is crucial for both forensic and research applications.