1350910-16-5

Basic information

• Product Name: tert-butyl (3R,4R,αS)-3-[N-3',4'-dimethoxybenzyl-N-(α-methylbenzyl)amino]-4-(N,N-dibenzylamino)pentanoate
• Synonyms: tert-butyl (3R,4R,αS)-3-[N-3',4'-dimethoxybenzyl-N-(α-methylbenzyl)amino]-4-(N,N-dibenzylamino)pentanoate
• CAS NO: 1350910-16-5
• Molecular Weight: 622.848
• Mol File: 1350910-16-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (3R,4R,αS)-3-[N-3',4'-dimethoxybenzyl-N-(α-methylbenzyl)amino]-4-(N,N-dibenzylamino)pentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (3R,4R,αS)-3-[N-3',4'-dimethoxybenzyl-N-(α-methylbenzyl)amino]-4-(N,N-dibenzylamino)pentanoate(1350910-16-5)
• EPA Substance Registry System: tert-butyl (3R,4R,αS)-3-[N-3',4'-dimethoxybenzyl-N-(α-methylbenzyl)amino]-4-(N,N-dibenzylamino)pentanoate(1350910-16-5)

Safety Data

• Hazardous Substances Data: 1350910-16-5(Hazardous Substances Data)

Upstream product

• 129286-74-4 (+/-)-N,N-dibenzylalaninal 
• 100-39-0 benzyl bromide 
• 60448-81-9 (+/-)-N,N-dibenzyl-2-aminopropan-1-ol 
• 1350909-96-4 tert-butyl (RS,E)-4-(N,N-dibenzylamino)pent-2-enoate 
• 38235-77-7 (R)-N-benzyl-1-phenylethylamine 
• 308273-67-8 (S)-N-3,4-dimethoxybenzyl-N-(α-methylbenzyl)amine 

Relevant articles and documents

Parallel kinetic resolution of acyclic γ-amino-α,β- unsaturated esters: Application to the asymmetric synthesis of 4-aminopyrrolidin-2-ones

Conjugate addition of a 50:50 pseudoenantiomeric mixture of lithium (R)-N-benzyl-N-(α-methylbenzyl)amide and lithium (S)-N-3,4- dimethoxybenzyl-N-(α-methylbenzyl)amide to a range of racemic acyclic γ-amino-α,β-unsaturated esters (derived from the corresponding α-amino acids) effects their efficient parallel kinetic resolution, allowing the preparation of enantiopure β,γ-diamino esters. The β,γ-diamino ester products of these reactions are readily converted into the corresponding substituted 4-aminopyrrolidin-2-ones via N-debenzylation and cyclization.