1351125-34-2

Basic information

• Product Name: C₂₇H₂₈FN₃O₆
• CAS NO: 1351125-34-2
• Molecular Weight: 509.534
• Mol File: 1351125-34-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₇H₂₈FN₃O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₂₈FN₃O₆(1351125-34-2)
• EPA Substance Registry System: C₂₇H₂₈FN₃O₆(1351125-34-2)

Safety Data

• Hazardous Substances Data: 1351125-34-2(Hazardous Substances Data)

Upstream product

• 179688-27-8 ethyl 2-amino-4,5-bis(2-methoxyethoxy)-benzoate 
• 1351124-92-9 2-hydroxy-4,5-bis(2-methoxy-ethoxy)benzoic acid 
• 202197-31-7 1-(3-fluorobenzyl)-1H-indazol-5-ylamine 

Relevant articles and documents

Synthesis and biological evaluation of a series of novel salicylanilides as inhibitors of EGFR protein tyrosine kinases

The synthesis and biological evaluation of two series of salicylanilide derivatives on the EGFR and ErbB-2 tyrosine kinases inhibitory activities were conducted. Of the tested compounds those having an additional aryl group substituted on the anilino ring were active on the EGFR tyrosine kinase inhibition (7a-c and 13a, 13c, 13d, 13f). The inhibitory activities were all in the low micromolar or submicromolar range. In addition, compound 13a was found to have dual inhibitory activities both on EGFR and ErbB-2 tyrosine kinases (1.654 ± 1.280 and 7.134 ± 1.265 μmol/L).