1352240-97-1Relevant articles and documents
A one-pot green synthesis of alkylidenesuccinimides
Yan, Lin,Yang, Wenguo,Li, Lixin,Shen, Yang,Jiang, Zhiyong
, p. 1906 - 1910 (2011)
A mild and facile Wittig reaction between N-substituted maleimides and aldehydes has been developed. Various synthetically valuable alkylidenesuccinimides were obtained from this one-pot reaction in high yields (up to 99%). The product was obtained by simple filtration and no extra purification was necessary. Ethanol, an environment-benign solvent, was found to be a suitable reaction medium. We have developed a mild and convenient one-pot Wittig reaction for the green synthesis of alkylidenesuccinimides. Under the established reaction conditions, a number of various synthetically valuable alkylidenesuccinimides were obtained in high yields (up to 99%). Copyright