13524-74-8

Basic information

• Product Name: 2-Propanol, 2-methyl-1-phenoxy-
• CAS NO: 13524-74-8
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• Mol File: 13524-74-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Propanol, 2-methyl-1-phenoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanol, 2-methyl-1-phenoxy-(13524-74-8)
• EPA Substance Registry System: 2-Propanol, 2-methyl-1-phenoxy-(13524-74-8)

Safety Data

• Hazardous Substances Data: 13524-74-8(Hazardous Substances Data)

Upstream product

• 558-30-5 2-methyl-1,2-epoxypropane 
• 108-95-2 phenol 
• 917-64-6 methyl magnesium iodide 
• 621-87-4 3-phenoxy-2-propanone 
• 2555-49-9 phenoxyacetic acid ethyl ester 
• 75-16-1 methylmagnesium bromide 
• 2065-23-8 methyl 2-phenoxyacetate 
• 558-42-9 3-chloro-2-methylpropan-2-ol 
• 15895-57-5 2,3-Epoxy-2-methyl-1-phenoxypropane 
• 1072160-11-2 1-[(1,1-dimethyl-2-phenoxyethoxy)methyl]-4-methoxybenzene 

Downstream Products

• 16654-59-4 2-Phenoxy-1,1-dimethyl-aethyl-(trimethylsilylaether) 
• 5842-34-2 (+/-)-2,2-dimethyl-3c-phenoxy-cyclopropane-r-carboxylic acid 
• 5842-34-2 (+/-)-2,2-dimethyl-3t-phenoxy-cyclopropane-r-carboxylic acid 
• 5863-13-8 ethyl 2,2-dimethyl-3-phenoxycyclopropane-1-carboxylate 
• 5863-19-4 2-(2,2-dimethyl-3-phenoxy-cyclopropyl)-oct-3-yn-2-ol 
• 5842-58-0 1-(1-Hydroxy-1-phenyl-ethyl)-2,2-dimethyl-3-phenoxy-cyclopropan 
• 5842-60-4 2-(2,2-dimethyl-3-phenoxy-cyclopropyl)-but-3-yn-2-ol 
• 5842-63-7 2-(2,2-dimethyl-3-phenoxy-cyclopropyl)-but-3-en-2-ol 
• 5842-55-7 1-Acetyl-2,2-dimethyl-3-phenoxy-cyclopropan 
• 5842-47-7 2-(2,2-dimethyl-3-phenoxy-cyclopropyl)-propan-2-ol 
• 5842-59-1 1-(2,2-dimethyl-3-phenoxy-cyclopropyl)-ethanol 
• 5842-35-3 (2,2-dimethyl-3-phenoxy-cyclopropyl)-methanol 
• 5842-48-8 3-Phenoxy-2,2-dimethyl-cyclopropyl-diphenyl-methanol 
• 5820-20-2 ((2-methylprop-1-en-1-yl)oxy)benzene 

Relevant articles and documents

Palladium-Catalyzed C(sp3)?H Arylation of Primary Amines Using a Catalytic Alkyl Acetal to Form a Transient Directing Group

C?H Functionalization of amines is a prominent challenge due to the strong complexation of amines to transition metal catalysts, and therefore typically requires derivatization at nitrogen with a directing group. Transient directing groups (TDGs) permit C?H functionalization in a single operation, without needing these additional steps for directing group installation and removal. Here we report a palladium catalyzed γ-C?H arylation of amines using catalytic amounts of alkyl acetals as transient activators (e.g. commercially available (2,2-dimethoxyethoxy)benzene). This simple additive enables arylation of amines with a wide range of aryl iodides. Key structural features of the novel TDG are examined, demonstrating an important role for the masked carbonyl and ether functionalities. Detailed kinetic (RPKA) and mechanistic investigations determine the order in all reagents, and identify cyclopalladation as the turnover limiting step. Finally, the discovery of an unprecedented off-cycle free-amine directed ?-cyclopalladation of the arylation product is reported.

Palladium Catalyzed, Regioselective Reduction of 1,2-Epoxides by Ammonium Formate

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Compounds having one or more aminosulfaonyloxy radicals useful as pharmaceuticals

Methods of treating chronic arthritis and osteoporosis which utilize both known and novel compounds which would fall under the general formula:(HO)p--A--[--OS(O) 2 NR 1 R 2 ] zwherein A encompasses a wide range of values including but not limited to aryl, loweralkyl, cycloalkyl, and carbohydrates including sucrose and fructose; p is equal to the number of unreacted hydroxy groups contained on the molecule and may be zero; z is the number of --OS(O) 2 NR 1 R 2 groups and is always at least one; R 1 and R 2 are selected from hydrogen, loweralkyl, carboxy and the like; a novel process for preparing the compounds is provided wherein an appropriate sulfamic acid aryl ester is reacted with a hydroxy substituted A radical which may or may not contain thereon protected carboxyl, amino or hydroxy substituents, in an aprotic solvent containing a tertiary amine base. Pharmaceutical compositions for the treatment of chronic arthritis and osteoporosis are also provided.