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135249-30-8

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135249-30-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 135249-30-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,2,4 and 9 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 135249-30:
(8*1)+(7*3)+(6*5)+(5*2)+(4*4)+(3*9)+(2*3)+(1*0)=118
118 % 10 = 8
So 135249-30-8 is a valid CAS Registry Number.

135249-30-8Relevant articles and documents

An expedient synthesis of novel 2-substituted thiazolo[4,5-f]isoquinolines/ quinolines and benzo[1,2-d:4,3-d']bisthiazoles and their potential as inhibitors of COX-1 and COX-2

Chakrabarty, Manas,Mukherji, Ajanta,Karmakar, Sulakshana,Mukherjee, Ratna,Nagai, Kenichiro,Geronikaki, Athina,Elenic, Pitta

experimental part, p. 265 - 290 (2011/02/24)

An efficient, general synthesis of 2-substituted thiazolo[4,5-f] isoquinolines, thiazolo[4,5-f]-quinolines and benzo[1,2-d:4,3-d']bisthiazoles has been accomplished from 5-nitroisoquinoline/quinoline and 6-nitrobenzothiazole, respectively, and all the products have been thoroughly identified spectroscopically (IR, 1H and 13C NMR, LR/HR EI/FAB/ESI-MS). The synthesis of thiazolo[4,5-f]isoquinolines constitutes the first synthesis of this class of heteroarenes. Eighteen compounds, covering all three types, were screened for inhibition of COX-1 and COX-2, and some of them showed moderate activities. ARKAT-USA, Inc.

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