135308-74-6 Usage
Description
D,L N,O-Didesmethylvenlafaxine, a secondary amino compound, is a metabolite of Venlafaxine, a selective serotonin noradrenaline reuptake inhibitor. It is characterized by the presence of a 1-hydroxycyclohexyl and a 4-hydroxyphenyl group at position 1 of the N-methylethanamine structure. This white solid is known for its role in the metabolism of the parent drug, Venlafaxine.
Uses
Used in Pharmaceutical Industry:
D,L N,O-Didesmethylvenlafaxine is used as a metabolite in the pharmaceutical industry for understanding the metabolic pathways and pharmacokinetics of Venlafaxine. This knowledge aids in optimizing the drug's efficacy, safety, and dosing regimens.
Used in Research and Development:
In the field of research and development, D,L N,O-Didesmethylvenlafaxine serves as a crucial compound for studying the mechanisms of action, potential side effects, and interactions with other drugs or substances. This information is vital for the development of new drugs with improved therapeutic profiles and reduced side effects.
Used in Quality Control and Drug Analysis:
D,L N,O-Didesmethylvenlafaxine is utilized as a reference compound in quality control and drug analysis to ensure the purity, potency, and consistency of Venlafaxine-containing products. This application helps maintain the safety and efficacy of medications containing Venlafaxine.
Used in Drug Metabolism Studies:
In the field of drug metabolism, D,L N,O-Didesmethylvenlafaxine is used to investigate the metabolic enzymes, pathways, and genetic factors that influence the conversion of Venlafaxine to its active metabolites. This research contributes to personalized medicine by identifying individual variations in drug response and metabolism.
Used in Toxicology and Safety Assessment:
D,L N,O-Didesmethylvenlafaxine is employed in toxicology and safety assessment to evaluate the potential toxic effects and safety profile of Venlafaxine and its metabolites. This information is essential for determining the safe dosage ranges and monitoring the potential adverse effects of the drug in clinical practice.
Check Digit Verification of cas no
The CAS Registry Mumber 135308-74-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,3,0 and 8 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 135308-74:
(8*1)+(7*3)+(6*5)+(5*3)+(4*0)+(3*8)+(2*7)+(1*4)=116
116 % 10 = 6
So 135308-74-6 is a valid CAS Registry Number.
InChI:InChI=1/C15H23NO2/c1-16-11-14(12-5-7-13(17)8-6-12)15(18)9-3-2-4-10-15/h5-8,14,16-18H,2-4,9-11H2,1H3
135308-74-6Relevant articles and documents
Desvenlafaxine succinate impurities as well as preparation method and use thereof
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Paragraph 0045, (2018/06/15)
The invention discloses desvenlafaxine succinate impurities, i.e., desvenlafaxine succinate impurity 2 and desvenlafaxine succinate impurity I. In addition, the invention further discloses a preparation method of a desvenlafaxine succinate impurity 2, a desvenlafaxine succinate impurity 5, a desvenlafaxine succinate impurity 6, a desvenlafaxine succinate impurity 7, a desvenlafaxine succinate impurity H and a desvenlafaxine succinate impurity I. According to the desvenlafaxine succinate related impurities and preparation thereof, provided by the invention, a foundation for quality research onintermediates, raw pharmaceutical materials and compositions of desvenlafaxine succinate is laid.
