135397-32-9Relevant articles and documents
Synthesis and antiviral activity of 4-benzyl pyridinone derivatives as potent and selective non-nucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitors
Dolle,Nguyen, Chi Hung,Legraverend,Aubertin,Kirn,Andreola,Ventura,Tarrago-Litvak,Bisagni
, p. 3949 - 3962 (2007/10/03)
Several 4-benzyl analogues of 5-ethyl-6-methyl-4-(phenylthio)pyridin-2(1H)-ones were synthesized and evaluated for their anti-HIV-1 activities. Key transformations include metalation at the 4-C-position of 5-ethyl-2-methoxy-6-methyl-3-pivaloylaminopyridin