1354943-30-8

Basic information

• Product Name: C₁₄H₁₅Br₃N₄O₂
• Synonyms: C₁₄H₁₅Br₃N₄O₂
• CAS NO: 1354943-30-8
• Molecular Weight: 511.011
• Mol File: 1354943-30-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₅Br₃N₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₅Br₃N₄O₂(1354943-30-8)
• EPA Substance Registry System: C₁₄H₁₅Br₃N₄O₂(1354943-30-8)

Safety Data

• Hazardous Substances Data: 1354943-30-8(Hazardous Substances Data)

Upstream product

• 1354943-40-0 N-hydroxyhept-6-ynamide 
• 54459-64-2 2,4,6-tribromo-1-(bromomethyl)benzene 
• 30964-00-2 hept-6-ynoic acid 

Relevant articles and documents

Design, synthesis, and biological evaluation of novel histone deacetylase 1 inhibitors through click chemistry

We report the design, synthesis, and biological evaluation of a new series of HDAC1 inhibitors using click chemistry. Compound 17 bearing a phenyl ring at meta-position was identified to show much better selectivity for HDAC1 over HDAC7 than SAHA. The compond 17 also showed better in vitro anticancer activities against several cancer cell lines than that of SAHA. This work could serve as a foundation for further exploration of selective HDAC inhibitors using the compound 17 molecular scaffold.