1354962-25-6

Basic information

• Product Name: 2-(4-chloro-3-(trifluoromethyl)phenoxy)-5-formylbenzonitrile
• Synonyms: 2-(4-chloro-3-(trifluoromethyl)phenoxy)-5-formylbenzonitrile
• CAS NO: 1354962-25-6
• Molecular Weight: 325.674
• Mol File: 1354962-25-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-(4-chloro-3-(trifluoromethyl)phenoxy)-5-formylbenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chloro-3-(trifluoromethyl)phenoxy)-5-formylbenzonitrile(1354962-25-6)
• EPA Substance Registry System: 2-(4-chloro-3-(trifluoromethyl)phenoxy)-5-formylbenzonitrile(1354962-25-6)

Safety Data

• Hazardous Substances Data: 1354962-25-6(Hazardous Substances Data)

Upstream product

• 6294-93-5 4-chloro-3-trifluoromethylphenol 
• 218301-22-5 2-fluoro-5-formylbenzonitrile 

Downstream Products

• 1369254-89-6 2-{[4-chloro-3-(trifluoromethyl)phenyl]oxy}-5-ethenylbenzonitrile 
• 1380429-77-5 5-(chloromethyl)-2-{[4-chloro-3-(trifluoromethyl)phenyl]oxy}benzonitrile 
• 1369254-90-9 2-[(4-{[4-chloro-3-(trifluoromethyl)phenyl]oxy}phenyl)oxy]-5-(2-hydroxyethyl)benzonitrile 
• 1381791-23-6 2-{[4-chloro-3-(trifluoromethyl)phenyl]oxy}-5-{[(2-oxo-2,3-dihydro-4-pyrimidinyl)oxy]methyl}benzonitrile 
• 1381791-99-6 5-{[(2-chloro-4-pyrimidinyl)oxy]methyl}-2-{[4-chloro-3-(trifluoromethyl)phenyl]oxy}benzonitrile 
• 1381791-20-3 2-{[4-chloro-3-(trifluoromethyl)phenyl]oxy}-5-({[2-oxo-1-(2-pyridinylmethyl)-1,2-dihydro-4-pyrimidinyl]oxy}methyl)benzonitrile 
• 1369255-73-1 2-(4-chloro-3-(trifluoromethyl)phenoxy)-5-(hydroxymethyl)benzylnitrile 
• 1381792-06-8 C₂HF₃O₂*C₁₅H₁₀ClF₃N₂O 

Relevant articles and documents

COMPOUNDS

The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example Alzheimer's disease.

BICYCLIC PYRIMIDONE COMPOUNDS

The present invention relates to novel bicyclic pyrimidone compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.

2,3-DIHYDROIMIDAZO[1,2-C] PYRIMIDIN-5(1H)-ONE COMPOUNDS USE AS LP-PLA2 INHIBITORS

Disclosed are 2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one compounds that inhibit Lp-PLA2, processes for their preparation, compositions containing them and their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer?s disease