1355326-21-4 Usage
General Description
Mutant IDH1-IN-1 is a chemical compound that has been developed as a potential inhibitor of the mutant isocitrate dehydrogenase 1 (IDH1) enzyme. Mutations in the IDH1 gene are known to play a role in the development of certain types of cancer, particularly gliomas. By inhibiting the mutant IDH1 enzyme, Mutant IDH1-IN-1 has the potential to block the abnormal production of 2-hydroxyglutarate, a metabolite that is associated with cancer progression. Mutant IDH1-IN-1 has shown promising results in preclinical studies, demonstrating its potential as a targeted therapy for cancer treatment. Further research and clinical trials are needed to determine the safety and efficacy of Mutant IDH1-IN-1 as a potential cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 1355326-21-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,5,3,2 and 6 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1355326-21:
(9*1)+(8*3)+(7*5)+(6*5)+(5*3)+(4*2)+(3*6)+(2*2)+(1*1)=144
144 % 10 = 4
So 1355326-21-4 is a valid CAS Registry Number.
1355326-21-4Relevant articles and documents
THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE
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Page/Page column 148-149, (2012/02/02)
Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1 comprising administering to a subject in need thereof a compound described here.
