1356679-57-6

Basic information

• Product Name: (2-(4-(1,3-dioxan-2-yl)-2-fluorophenyl)benzo[d]thiazol-6-yl)(2-ethylthiazolidin-3-yl)methanone
• Synonyms: (2-(4-(1,3-dioxan-2-yl)-2-fluorophenyl)benzo[d]thiazol-6-yl)(2-ethylthiazolidin-3-yl)methanone
• CAS NO: 1356679-57-6
• Molecular Weight: 458.578
• Mol File: 1356679-57-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-(4-(1,3-dioxan-2-yl)-2-fluorophenyl)benzo[d]thiazol-6-yl)(2-ethylthiazolidin-3-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-(4-(1,3-dioxan-2-yl)-2-fluorophenyl)benzo[d]thiazol-6-yl)(2-ethylthiazolidin-3-yl)methanone(1356679-57-6)
• EPA Substance Registry System: (2-(4-(1,3-dioxan-2-yl)-2-fluorophenyl)benzo[d]thiazol-6-yl)(2-ethylthiazolidin-3-yl)methanone(1356679-57-6)

Safety Data

• Hazardous Substances Data: 1356679-57-6(Hazardous Substances Data)

Upstream product

• 81171-71-3 4-bromo-2-fluoro-1-isothiocyanato-benzene 
• 367-24-8 4-bromo-2-fluoroaniline 
• 1356679-53-2 ethyl 2-(4-(1,3-dioxan-2-yl)-2-fluorophenyl)benzo[d]thiazole-6-carboxylate 
• 1202076-30-9 2-(4-(1,3-dioxan-2-yl)-2-fluorophenyl)-6-bromobenzo[d]thiazole 
• 1356679-50-9 N-(4-bromo-2-fluorophenyl)-4-(1,3-dioxan-2-yl)-2-fluorobenzothioamide 

Downstream Products

• 1356679-58-7 methyl 1-(4-(6-(2-ethylthiazolidine-3-carbonyl)benzo[d]thiazol-2-yl)-3-fluorobenzyl)azetidine-3-carboxylate 
• 1365997-55-2 methyl 1-(4-(6-((R)-2-ethylthiazolidine-3-carbonyl)benzo[d]thiazol-2-yl)-3-fluorobenzyl)azetidine-3-carboxylate 
• 1365998-75-9 methyl 1-(4-(6-((S)-2-ethylthiazolidine-3-carbonyl)benzo[d]thiazol-2-yl)-3-fluorobenzyl)azetidine-3-carboxylate 
• 1365997-38-1 C₂₀H₁₇FN₂O₂S₂ 

Relevant articles and documents

Novel 5- and 6-subtituted benzothiazoles with improved physicochemical properties: Potent S1P1 agonists with in vivo lymphocyte-depleting activity

An SAR campaign designed to increase polarity in the 'tail' region of benzothiazole 1 resulted in two series of structurally novel 5-and 6-substituted S1P1 agonists. Structural optimization for potency ultimately delivered carboxamide (+)-11f,