1360934-51-5

Basic information

• Product Name: Methyl 2-chloro-5-(trifluoroMethyl)nicotinate
• Synonyms: Methyl 2-chloro-5-(trifluoroMethyl)nicotinate;2-Chloro-5-trifluoromethyl-nicotinic acid methyl ester
• CAS NO: 1360934-51-5
• Molecular Formula: C₈H₅ClF₃NO₂
• Molecular Weight: 239.5790096
• Mol File: 1360934-51-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 254.1±40.0 °C(Predicted)
• Appearance: /
• Density: 1.443±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -4.10±0.10(Predicted)
• CAS DataBase Reference: Methyl 2-chloro-5-(trifluoroMethyl)nicotinate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-chloro-5-(trifluoroMethyl)nicotinate(1360934-51-5)
• EPA Substance Registry System: Methyl 2-chloro-5-(trifluoroMethyl)nicotinate(1360934-51-5)

Safety Data

• Hazardous Substances Data: 1360934-51-5(Hazardous Substances Data)

Usage

Description

Methyl 2-chloro-5-(trifluoromethyl)nicotinate is a chemical compound with the molecular formula C9H6ClF3NO2. It is a derivative of nicotinic acid and contains a methyl group, a chlorine atom, and a trifluoromethyl group attached to the nicotinate core. This white to off-white crystalline powder is sparingly soluble in water but soluble in most organic solvents. It is often used in organic synthesis as a building block for the preparation of various pharmaceutical and agrochemical compounds.

Uses

Used in Pharmaceutical Industry:
Methyl 2-chloro-5-(trifluoromethyl)nicotinate is used as a building block for the synthesis of various pharmaceutical compounds. Its unique structure and functional groups make it a valuable intermediate in the development of new drugs.
Used in Agrochemical Industry:
Methyl 2-chloro-5-(trifluoromethyl)nicotinate is also used as a building block for the preparation of agrochemical compounds. Its potential applications in this industry contribute to the development of new pesticides and other agricultural chemicals.
Used in Research and Development:
Methyl 2-chloro-5-(trifluoromethyl)nicotinate has potential applications in research and development within the pharmaceutical industry. Its unique properties and reactivity make it a promising candidate for the exploration of new drug candidates and the advancement of chemical synthesis techniques.

Upstream product

• 505084-59-3 2-chloro-5-(trifluoromethyl)pyridine-3-carboxylic acid 
• 74-88-4 methyl iodide 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 67-56-1 methanol 

Relevant articles and documents

PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS

Compounds of the formula (I) wherein the substituents are as defined in claim 1. Furthermore, the present invention relates to agrochemical compositions which comprise compounds of formula (I), to preparation of these compositions, and to the use of the compounds or compositions in agriculture or horticulture for combating, preventing or controlling animal pests, including arthropods and in particular insects, nematodes, molluscs or representatives of the order Acarina.

2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS

The present invention relates to Nav1.8 Inhibitor 2,3-dihydroquinazolin compounds of Formula (X); wherein Y', X', B', R1', R2', R3', R5', R6', R7', and z1 are as defined herein; or pharmaceutically acceptable salts or tautomer forms thereof, corresponding pharmaceutical compositions or formulations, methods or processes of compound preparation, methods, compounds for use in, uses for and/or combination therapies for treating pain and/or pain-related or associated disease(s), disorder(s) or condition(s), respectively.

NOVEL AMINE DERIVATIVE OR SALT THEREOF

A novel amine derivative expressed by general formula (1) (in the formula: G1, G2, and G3 are the same or different and represent CH or a nitrogen atom; R1 represents a chlorine atom, an optionally-substituted C3-8 cycloalkyl group, or the like; R2 represents -COOR5 (in the formula, R5 represents a hydrogen atom or a carboxyl protective group), or the like; R3 represents a hydrogen atom, or the like; and R4 represents an optionally-substituted condensed bicyclic hydrocarbon group, an optionally-substituted bicyclic heterocyclic group, or the like), or a salt thereof is useful in procedures such as the treatment or prevention of conditions related to excessive keratinocyte proliferation.