1361130-80-4Relevant articles and documents
Guest inclusion in cyclic imides containing flexible tethers
Singh, Devendra,Baruah, Jubaraj B.
, p. 269 - 281 (2013/07/26)
Guest inclusion properties of two cyclic imides which have carboxylic acids connected through flexible tether, namely, 4-(1,3-dioxo-1,3-dihydro-isoindol-2- ylmethyl)-cyclohexanecarboxylic acid (1) and 4-(1,3-dioxo-1H,3H-benzo[de] isoquinolin-2-ylmethyl)-cyclohexanecarboxylic acid (2) are studied. The crystals of host 1 containing one molecule of 1, the crystals of 4,4′-bipyridine (bpy) cocrystal of 1 containing one molecule of 1 and half molecule of bpy (1a), the crystals of 1,4-dioxane solvate of 1 containing two molecule of 1 and one and half molecule of 1,4-dioxane (1b) and the crystals of quinoline solvate of 1 containing one molecule of 1 and one molecule of quinoline (1c) in their crystallographic asymmetric units are investigated. Intermolecular hydrogen bonded two dimensional (2D) sheet structure of 1 and 3D channel network of 1b are comprised of cyclic R 2 2 (8) hydrogen bond motifs; whereas cleavage of dimeric carboxylic acid R 2 2 (8) motifs occurs in the structures of 1a and 1c in which 3D host-guest networks are comprised of discrete O-H···N and cyclic R 2 2 (7) interactions, respectively. Various types of weak interactions between the two symmetry nonequivalent host molecule are found to be responsible for the formation of channels (14 × 11 A) filled by guest 1,4-dioxane molecules in the crystal lattice of 1b. Two different solvates of 2 containing one molecule of 2 with a water molecule (2a) and one molecule of 2 with a quinoline molecule (2b) in their crystallographic asymmetric units, respectively, are also crystallized in different space groups. The quinoline molecules are held with host molecules by discrete O-H···N and C-H···O interactions and reside inside the voids formed by 3D repeated hexameric assemblies of host molecules in the crystal lattice of 2b.
