136144-59-7

Basic information

• Product Name: Cytidine, 2'-deoxy-5-phenyl-
• CAS NO: 136144-59-7
• Molecular Formula: C15H17N3O4
• Molecular Weight: 303.318
• Mol File: 136144-59-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Cytidine, 2'-deoxy-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Cytidine, 2'-deoxy-5-phenyl-(136144-59-7)
• EPA Substance Registry System: Cytidine, 2'-deoxy-5-phenyl-(136144-59-7)

Safety Data

• Hazardous Substances Data: 136144-59-7(Hazardous Substances Data)

Upstream product

• 611-53-0 5-Iodo-2'-deoxycytidine 
• 98-80-6 phenylboronic acid 
• 591-50-4 iodobenzene 
• 65523-09-3 5-(chloromercuri)-2'-deoxycytidine 
• 3992-42-5 2'-deoxycytidine monohydrochloride 

Downstream Products

• 1044218-88-3 4-N-acetyl-5-phenyl-2'-deoxycytidine 

Relevant articles and documents

Water-Soluble Pd-Imidate Complexes: Broadly Applicable Catalysts for the Synthesis of Chemically Modified Nucleosides via Pd-Catalyzed Cross-Coupling

(Figure Presented) A broadly applicable catalyst system consisting of water-soluble Pd-imidate complexes has been enployed for the Suzuki-Miyaura cross-coupling of four different nucleosides in water under mild conditions. The efficient nature of the catalyst system also allowed its application in developing a microwave-assisted protocol with the purpose of expediting the catalytic reaction. Preliminary mechanistic studies, assisted by catalyst poison tests and stoichiometric tests performed using an electrospray ionization spectrometer, revealed the possible presence of a homotopic catalyst system.

PALLADIUM CATALYZED COUPLING REACTION FOR THE SYNTHESIS OF C-5 ARYL AND HETEROARYL SUBSTITUTED 2'-DEOXYCYTIDINE

Cytosine nucleosides substituted at C-5 with differently substituted aryls and heteroaryls have been prepared via a palladium catalyzed reaction utilizing 5-chloromercuri or acetoxymercuri nucleosides and haloarenes or heteroarenes.