13620-59-2

Basic information

• Product Name: 3-Phenyl-1-(4-nitro-phenyl)-4-nitro-butan-1-on
• Synonyms: 3-Phenyl-1-(4-nitro-phenyl)-4-nitro-butan-1-on
• CAS NO: 13620-59-2
• Molecular Weight: 314.298
• Mol File: 13620-59-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-Phenyl-1-(4-nitro-phenyl)-4-nitro-butan-1-on(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenyl-1-(4-nitro-phenyl)-4-nitro-butan-1-on(13620-59-2)
• EPA Substance Registry System: 3-Phenyl-1-(4-nitro-phenyl)-4-nitro-butan-1-on(13620-59-2)

Safety Data

• Hazardous Substances Data: 13620-59-2(Hazardous Substances Data)

Upstream product

• 75-52-5 nitromethane 
• 20432-02-4 1-(4-nitro-phenyl)-3-phenyl-propenone 
• 20432-02-4 (E)-4'-nitrochalcone 
• 5153-67-3 nitrostyrene 
• 100-19-6 (4-nitrophenyl)ethanone 
• 102-96-5 (2-nitroethenyl)benzene 
• 38502-65-7 1-(4-nitrophenyl)-3-(4-methoxyphenyl)propane-1,3-dione 

Relevant articles and documents

Sequential Michael addition/retro-Claisen condensation of 1,3-diarylpropan-1,3-diones with nitrostyrenes: one-step synthesis of 4-nitro-1,3-diarylbutan-1-ones

Abstract : The sequential Michael addition/retro-Claisen condensation of 1,3-diarylpropan-1,3-diones with nitrostyrenes is described. 4-Nitro-1,3-diarylbutan-1-ones were efficiently synthesized in good to high yield under mild, transition-metal-free condition. This one-step method involving sequential carbon-carbon bond formation and cleavage provides a good alternative to the synthesis of various γ-nitro ketones. Graphical abstract: The sequential Michael addition/retro-Claisen condensation of 1,3-diarylpropan-1,3-diones with nitrostyrenes is described. 4-Nitro-1,3-diarylbutan-1-ones were efficiently synthesized in good to high yield under mild and transition-metal-free condition. [Figure not available: see fulltext.].

New synthesis of 1,3-diaryl-4-nitro-1-butanones by microwave-promoted Michael addition of nitromethane to chalcones without solvent

The Michael addition of nitromethane to chalcones promoted by microwave irradiation without solvent afforded 1,3-diaryl-4-nitro-1-butanones in good yield. The products were characterised by IR, 1H NMR and elemental analysis.

MICHAEL ADDITIONS CATALYZED BY NICKEL(II) OR COBALT(II)ACETATE-2,2'-BIPYRIDINE COMPLEXES

In the presence of nickel(II) or cobalt(II)acetate-2,2'-bipyridine complexes, α,β-unsaturated ketones, methyl acrylate, and acrylonitrile were found to react with nitromethane, malononitrile, and aniline at room temperature under neutral condition to afford addition products in good yields.