1366384-12-4 Usage
Description
(2R)-1-(diphenylphosphino)-3,3-diMethyl-2-Butana, with the molecular formula C17H23P, is a chiral phosphine ligand that plays a significant role in organometallic chemistry and catalysis. (2R)-1-(diphenylphosphino)-3,3-diMethyl-2-Butana is known for its ability to coordinate with transition metals, forming stable complexes that are utilized in various metal-catalyzed reactions. Its structural features, including the bulky and symmetrical diphenylphosphino group, make it a valuable ligand for promoting stereoselectivity in metal-catalyzed reactions. The substituents on the 2-Butana backbone provide steric and electronic effects that enhance its reactivity and selectivity in catalytic processes. Overall, (2R)-1-(diphenylphosphino)-3,3-diMethyl-2-Butana is an important compound in the field of organometallic chemistry, contributing to the development of new catalytic methods and the synthesis of complex organic molecules.
Uses
Used in Organometallic Chemistry:
(2R)-1-(diphenylphosphino)-3,3-diMethyl-2-Butana is used as a chiral phosphine ligand for promoting stereoselectivity in metal-catalyzed reactions. Its bulky and symmetrical diphenylphosphino group, along with the steric and electronic effects of the substituents on the 2-Butana backbone, make it a valuable compound in this field.
Used in Catalysis:
(2R)-1-(diphenylphosphino)-3,3-diMethyl-2-Butana is used as a ligand in the development of new catalytic methods. Its ability to coordinate with transition metals and form stable complexes allows it to play a crucial role in various metal-catalyzed reactions, enhancing the reactivity and selectivity of catalytic processes.
Used in the Synthesis of Complex Organic Molecules:
(2R)-1-(diphenylphosphino)-3,3-diMethyl-2-Butana is employed as a key component in the synthesis of complex organic molecules. Its unique structural features and ability to coordinate with transition metals make it an important compound in the advancement of synthetic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1366384-12-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,6,3,8 and 4 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1366384-12:
(9*1)+(8*3)+(7*6)+(6*6)+(5*3)+(4*8)+(3*4)+(2*1)+(1*2)=174
174 % 10 = 4
So 1366384-12-4 is a valid CAS Registry Number.
1366384-12-4Relevant articles and documents
Asymmetric kinetic resolution of sulfides for the construction of unsymmetric sulfides and chiral 3,3-disubstituted oxindoles
Wang, Kaiye,Xiang, Yanan,Shi, Zhujun,Wang, Hongyu,Li, Na,Tang, Bo
, p. 6351 - 6354 (2019/07/10)
A range of 3,3-disubstituted oxindoles accessed using para-quinone methides derived from isatins with thiols were used for the formation of unsymmetrical disulfides, and 3,3-disubstituted oxindoles with a chiral quaternary carbon center and unsymmetric di
Tunable Bifunctional Phosphine-Squaramide Promoted Morita-Baylis-Hillman Reaction of N-Alkyl Isatins with Acrylates
Dong, Ze,Yan, Chao,Gao, Yongzhi,Dong, Chune,Qiu, Guofu,Zhou, Hai-Bing
, p. 2132 - 2142 (2015/06/23)
A series of highly tunable bifunctional phosphine-squaramide H-bond donor organocatalysts 6 has been synthesized from inexpensive and commercially available β-amino alcohols in moderate yields. Catalyst 6 can efficiently promote the asymmetric Morita-Baylis-Hillman (MBH) reaction of N-alkyl isatins with acrylate esters providing the chiral 3-substituted 3-hydroxy-2-oxindoles in good yields and enantioselectivities (up to 93 yield and 95 ee), in which the challenging substrate tert-butyl acrylate 9d, provided the best ee value to date. Moreover, this methodology was applied successfully in the synthesis of chiral cyclic spiropyrrolizidineoxindole and γ-butyrolactone derivatives without enantioselectivity deterioration. The possible mechanism of this MBH reaction was also investigated by 31PNMR, ESI-MS and KIE studies. The KIE experiments show that the electrophilic addition of N-methyl isatin to the complex of acrylate ester and phophine-squaramide is the rate-determing step of the asymmetric MBH reaction.
Synthesis of chiral aminophosphines from chiral aminoalcohols via cyclic sulfamidates
Guo, Rongwei,Lu, Shuiming,Chen, Xuanhua,Tsang, Chi-Wing,Jia, Wenli,Sui-Seng, Christine,Amoroso, Dino,Abdur-Rashid, Kamaluddin
supporting information; experimental part, p. 937 - 940 (2010/05/02)
(Chemical Equation Presented) Protic aminophosphines with multiple chiral centers were synthesized in good yields and high purity by the nucleophilic ring-opening of N-protected cyclic sulfamidates with metal phosphides, followed by hydrolysis and deprote
