1370349-51-1

Basic information

• Product Name: 2-amino-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(tritylsulfanyl)propionamide
• Synonyms: 2-amino-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(tritylsulfanyl)propionamide
• CAS NO: 1370349-51-1
• Molecular Weight: 498.646
• Mol File: 1370349-51-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-amino-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(tritylsulfanyl)propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(tritylsulfanyl)propionamide(1370349-51-1)
• EPA Substance Registry System: 2-amino-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(tritylsulfanyl)propionamide(1370349-51-1)

Safety Data

• Hazardous Substances Data: 1370349-51-1(Hazardous Substances Data)

Upstream product

• 406728-64-1 {1-[2-(3,4-dihydroxyphenyl)ethyl]carbamoyl-2-(tritylsulfanyl)ethyl}carbamic acid tert-butyl ester 
• 76-84-6 triphenylmethyl alcohol 
• 87242-61-3 2-tert-butoxycarbonylamino-3-(tritylsulfanyl)propionic acid 2,5-dioxopyrrolidin-1-yl ester 
• 2799-07-7 S-trityl-L-cysteine 
• 21947-98-8 N-tert-butyloxycarbonyl-S-trityl-L-cysteine 

Downstream Products

• 406727-56-8 3-(3,4-dihydroxyphenyl)-N-{1-[2-(3,4-dihydroxyphenyl)ethylcarbamoyl]-2-(tritylsulfanyl)ethyl}acrylamide 
• 1370349-53-3 2-[2-(3,4-dihydroxyphenyl)acetylamino]-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(tritylsulfanyl)propionamide 

Relevant articles and documents

Multifunctional imaging cross-linked stable nanometer drug-loading micelles and preparation method thereof

The present invention discloses multifunctional imaging cross-linked stable nanometer drug-loading micelles and a preparation method thereof. The preparation method comprises: adding 200 mg of an amphiphilic drug carrier mPEG-S-Trityl-Cys-Dopa and a hydrophobic anti-cancer drug to an organic solvent, dissolving, and carrying out dialysis by using a dialysis bag to remove free Fe; carrying out centrifugation, and filtering the supernatant by using a 0.45 [mu]m microporous filtration membrane; and carrying out freeze drying on the filtrate, wherein the freeze-dried product is the multifunctional imaging cross-linked stable nanometer drug-loading micelles mPEG-S-Trityl-Cys-Dopa-Fe/hydrophobic anti-cancer drug. According to the present invention, the obtained nanometer micelles have the stability and the pH-sensitivity, and can be visible by MRI, can break through the single-function mode of the traditional drug delivery system, can integrate the MRI imaging function and the drug carrier function, and can achieve the synchronous diagnosis and treatment of cancers.