137049-00-4

Basic information

• Product Name: 1-Methyl-1H-imidazole-4-sulfonyl chloride
• Synonyms: 1-Methyl-1H-imidazole-4-sulphonyl chloride;1-Methyl-1H-imidazole-4-sulfonyl chloride, 95+%;1H-Imidazole-4-sulfonylchloride,1-methyl-(9CI);1H-IMIDAZOLE-4-SULFONYLCHLORIDE,1-METHYL-;1-Methyl-1H-iMidazol-4-sulfonyl chloride;4-(Chlorosulphonyl)-1-methyl-1H-imidazole;BUTTPARK 27\06-11;1-METHYLIMIDAZOLE-4-SULFONYL CHLORIDE
• CAS NO: 137049-00-4
• Molecular Formula: C₄H₅ClN₂O₂S
• Molecular Weight: 180.61
• Product Categories: SULFONYLHALIDE;Imidazoles & Benzimidazoles;Sulphonyl Chlorides;Imidazoles & Benzimidazoles;Sulphonyl Chlorides;Heterocycles
• Mol File: 137049-00-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 88-91°C
• Boiling Point: 366.94 °C at 760 mmHg
• Flash Point: 175.719 °C
• Appearance: /
• Density: 1.605 g/cm³
• Vapor Pressure: 2.99E-05mmHg at 25°C
• Refractive Index: 1.621
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• Solubility: DMSO (Slightly)
• PKA: 0.18±0.70(Predicted)
• Sensitive: Moisture Sensitive
• Stability: Moisture Sensitive
• CAS DataBase Reference: 1-Methyl-1H-imidazole-4-sulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-1H-imidazole-4-sulfonyl chloride(137049-00-4)
• EPA Substance Registry System: 1-Methyl-1H-imidazole-4-sulfonyl chloride(137049-00-4)

Safety Data

• Hazard Codes: Xi,C
• Statements: 34-29-14-36-20/21/22
• Safety Statements: 26-36/37/39-8-45-30-22
• RIDADR: 3261
• HazardClass: 8
• Hazardous Substances Data: 137049-00-4(Hazardous Substances Data)

Usage

General Description

1-Methyl-1H-Imidazole-4-Sulfonyl Chloride is a chemical compound with the molecular formula C5H6ClN2O2S. It is a sulfonyl chloride derivative of imidazole that is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. It is a highly reactive compound that is used as a reagent in organic synthesis to introduce the 1-methyl-1H-imidazol-4-ylsulfonyl group onto other molecules. Due to its reactivity and potential for forming hazardous byproducts, it must be handled and used with caution in a controlled laboratory setting. It is important to follow proper safety protocols and procedures when working with 1-Methyl-1H-Imidazole-4-Sulfonyl Chloride to prevent accidents and exposure to harmful substances.

InChI:InChI=1/C4H5ClN2O2S/c1-7-2-4(6-3-7)10(5,8)9/h2-3H,1H3

Upstream product

• 616-47-7 1-methyl-1H-imidazole 

Downstream Products

• 685534-33-2 1-methyl-1H-imidazole-4-sulfonic acid (5-chloro-2-[(E)-3-[(R)-4-(4-fluorobenzyl)-2-methyl-piperazin-1-yl]-3-oxo-propenyl]-phenyl)-amide 
• 690972-13-5 1-methyl-1H-imidazole-4-sulfonic acid {4-[2-(4-1,2-benzisothiazol-3-yl-piperazin-1-yl)-ethoxy]-phenyl}-amide 
• 702672-84-2 1-methyl-1H-imidazole-4-sulfonic acid [4-(5-bromo-4-prop-2-ynylamino-pyrimidin-2-ylamino)-phenyl]-amide 
• 640269-94-9 1-methyl-1H-imidazole-4-sulfonic acid {3-[4-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-piperidin-1-yl]-1-phenylpropyl}amide 
• 802905-05-1 3-[(4-chlorophenyl)thio]-2-methyl-4-[[(1-methyl-1H-imidazol-4-yl)sulfonyl]amino]-1H-indole-1-acetic acid ethyl ester 
• 444665-75-2 N-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3-(4-methoxybenzyl)-2-oxo-1,2,3,4-tetrahydroquinazolin-7-yl]-1-methyl-1H-imidazole-4-sulfonamide 

Relevant articles and documents

PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS

The present invention relates to compounds of formulae (I) and (II) which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-ones, 4-hydroxy-cycloalkyl[b]pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein R 10 and R 20 taken together are formulae (III) and (IV). STR1