1370642-72-0Relevant articles and documents
Synthesis of C3′ modified nucleosides for selective generation of the C3′-deoxy-3′-thymidinyl radical: A proposed intermediate in LEE induced DNA damage
Audat, Suaad A. S.,Trzasko Love, Cherylann,Al-Oudat, Buthina A. S.,Bryant-Friedrich, Amanda C.
experimental part, p. 3829 - 3837 (2012/06/29)
DNA damage pathways induced by low-energy electrons (LEEs) are believed to involve the formation of 2-deoxyribose radicals. These radicals, formed at the C3′ and C5′ positions of nucleotides, are the result of cleavage of the C-O phosphodiester bond throu