137330-52-0 Usage
Description
Voriconazole is a synthetic triazole antifungal medication that is effective against a wide range of fungal infections. It works by inhibiting the enzyme lanosterol 14α-demethylase, which is a key component in the biosynthesis of ergosterol, an essential component of the fungal cell membrane. This disruption in ergosterol synthesis leads to an accumulation of toxic intermediates and a weakened cell membrane, ultimately resulting in the death of the fungal cell.
Uses
Used in Pharmaceutical Industry:
Voriconazole is used as a systemic antifungal agent for the treatment of various fungal infections, including aspergillosis, candidiasis, and cryptococcal meningitis. It is particularly effective against filamentous fungi and yeasts, making it a valuable tool in the management of invasive fungal infections.
Used in Antifungal Treatments:
Voriconazole is used as an ergosterol biosynthesis inhibitor for the treatment of fungal infections caused by susceptible strains of fungi. By targeting the synthesis of ergosterol, Voriconazole disrupts the integrity of the fungal cell membrane, leading to the death of the fungal cells and clearing the infection.
Check Digit Verification of cas no
The CAS Registry Mumber 137330-52-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,3,3 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 137330-52:
(8*1)+(7*3)+(6*7)+(5*3)+(4*3)+(3*0)+(2*5)+(1*2)=110
110 % 10 = 0
So 137330-52-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3
