13734-66-2 Usage
Chemical structure
The compound consists of a ketone backbone (ethanone) with a bromophenyl group attached to the 2-position and a pyrrolidin-1-yl group attached to the 1-position.
Functional groups
The compound contains a carbonyl group (C=O) as the ketone functional group, a bromine atom as the halogen functional group, and a pyrrolidine ring as the nitrogen-containing heterocyclic functional group.
Physical properties
The physical properties of the compound are not provided in the material.
Chemical reactivity
The bromophenyl group can participate in halogenation reactions, and the pyrrolidin-1-yl group can participate in various organic reactions.
Uses
The compound is commonly used as a reagent in organic synthesis and pharmaceutical research, and may have potential applications in the development of new pharmaceuticals and agrochemicals.
Safety precautions
The compound may present health and safety hazards if not properly managed, so it is important to handle and use it with caution.
Check Digit Verification of cas no
The CAS Registry Mumber 13734-66-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,7,3 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 13734-66:
(7*1)+(6*3)+(5*7)+(4*3)+(3*4)+(2*6)+(1*6)=102
102 % 10 = 2
So 13734-66-2 is a valid CAS Registry Number.
13734-66-2Relevant articles and documents
Facile preparation of pyrimidinediones and thioacrylamides: Via reductive functionalization of amides
Trillo, Paz,Slagbrand, Tove,Tinnis, Fredrik,Adolfsson, Hans
supporting information, p. 9159 - 9162 (2017/08/17)
The development of an efficient protocol for the reductive functionalization of amides into pyrimidinediones and amino-substituted thioacrylamides is presented. Enamines are generated in a highly chemoselective amide hydrosilylation reaction catalyzed by
A chemoselective Reformatsky-Negishi approach to α-haloaryl esters
Wong, Brian,Linghu, Xin,Crawford, James J.,Drobnick, Joy,Lee, Wendy,Zhang, Haiming
, p. 1508 - 1515 (2014/02/14)
A practical synthesis of α-haloaryl esters has been achieved via a chemoselective Negishi coupling of poly-halogenated aromatics and Reformatsky reagents in the presence of catalytic Pd(dba)2 and Xantphos. This chemistry tolerates a variety of aryl halides and was successfully applied to the synthesis of Ibuprofen. The α-haloaryl ester products, exemplified by ethyl 2-(4-bromo-2-chlorophenyl)acetate (3a), can be further functionalized via palladium or copper catalysis to afford an array of α-aryl esters.
