1374227-69-6

Basic information

• Product Name: N′-(2-aminophenyl)-N′-phenylbenzohydrazide
• Synonyms: N′-(2-aminophenyl)-N′-phenylbenzohydrazide
• CAS NO: 1374227-69-6
• Molecular Weight: 303.363
• Mol File: 1374227-69-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N′-(2-aminophenyl)-N′-phenylbenzohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N′-(2-aminophenyl)-N′-phenylbenzohydrazide(1374227-69-6)
• EPA Substance Registry System: N′-(2-aminophenyl)-N′-phenylbenzohydrazide(1374227-69-6)

Safety Data

• Hazardous Substances Data: 1374227-69-6(Hazardous Substances Data)

Upstream product

• 532-96-7 N-benzoyl-N'-phenylhydrazine 
• 1493-27-2 ortho-nitrofluorobenzene 
• 51589-42-5 N′-(2-nitrophenyl)-N′-phenylbenzohydrazide 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 19818-44-1 1,4-Dihydro-1,3-diphenyl-1,2,4-benzotriazin 
• 19986-84-6 1,3-diphenyl-1,4-dihydrobenzo[e][1,2,4]triazin-4-yl 

Relevant articles and documents

Route to benzo- and pyrido-fused 1,2,4-triazinyl radicals via N ′-(Het)aryl- N ′-[2-nitro(het)aryl]hydrazides

A two-step route to 1,3-disubstituted benzo- and pyrido-fused 1,2,4-triazinyl radicals is presented. The route involves the N′-(2-nitroarylation) of easily prepared N′-(het)arylhydrazides via nucleophilic aromatic substitution of 1-halo-2-nitroarenes, which in most cases gives N′-(het)aryl-N′-[2-nitro(het)aryl]hydrazides in good yields. Mild reduction of the nitro group followed by an acid-mediated cyclodehydration gives the fused triazines, which upon alkali treatment afford the desired radicals. Fifteen examples of radicals are presented bearing a range of substituents at N-1, C-3, and C-7, including the pyrid-2-yl and 8-aza analogues. This route to the N′-(het)aryl-N′-[2-nitro(het)aryl]hydrazides, which works well with benzo- and picolinohydrazides, required a modification for aceto- and trifluoroacetohydrazides that involved a multistep synthesis of asymmetrically 1,1-diaryl-substituted hydrazines.