1374791-08-8

Basic information

• Product Name: 2-(4-phenoxyphenoxy)pyridine
• Synonyms: 2-(4-phenoxyphenoxy)pyridine
• CAS NO: 1374791-08-8
• Molecular Weight: 263.296
• Mol File: 1374791-08-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-phenoxyphenoxy)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-phenoxyphenoxy)pyridine(1374791-08-8)
• EPA Substance Registry System: 2-(4-phenoxyphenoxy)pyridine(1374791-08-8)

Safety Data

• Hazardous Substances Data: 1374791-08-8(Hazardous Substances Data)

Upstream product

• 109-04-6 2-bromo-pyridine 
• 831-82-3 4-Phenoxyphenol 

Downstream Products

• 269410-26-6 phenyl 4-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)]phenyl ether 
• 101-84-8 diphenylether 
• 41318-45-0 dimethyl(4-phenoxyphenyl)(phenyl)silane 
• 1374791-02-2 C₂₃H₂₄BNO₄ 

Relevant articles and documents

Rhodium-catalyzed borylation of aryl 2-pyridyl ethers through cleavage of the carbon-oxygen bond: Borylative removal of the directing group

The rhodium-catalyzed reaction of aryl 2-pyridyl ethers with a diboron reagent results in the formation of arylboronic acid derivatives via activation of the C(aryl)-O bonds. The straightforward synthesis of 1,2-disubstituted arenes was enabled through catalytic ortho C-H bond functionalization directed by the 2-pyridyloxy group followed by substitution of this group with a boryl group. Several control experiments revealed that the presence of a sp2 nitrogen atom at the 2-position of the substrate and the use of a boron-based reagent were crucial for the activation of the relatively inert C(aryl)-O bond of aryl 2-pyridyl ethers.