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1375405-22-3

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1375405-22-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1375405-22-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,5,4,0 and 5 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1375405-22:
(9*1)+(8*3)+(7*7)+(6*5)+(5*4)+(4*0)+(3*5)+(2*2)+(1*2)=153
153 % 10 = 3
So 1375405-22-3 is a valid CAS Registry Number.

1375405-22-3Upstream product

1375405-22-3Downstream Products

1375405-22-3Relevant articles and documents

ASPARTYL PROTEASE INHIBITORS

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Page 244-245, (2010/02/05)

The present invention provides compounds having formula (I): wherein R’, R0, R1, X1, R2, R3, R3’, X2, X3, and R4 are as defined herein, and pharmaceuticals compositions thereof. The present invention also provides methods of inhibiting proteases, more specially aspartyl proteases. In certain embodiments, compounds inhibit BACE (β-site APP-cleaving enzyme), and thus are useful in the treatment or prevention of a disease characterized by β-amyloid deposits in the brain (including, but not limited to, Alzheimer’s Disease). The present invention also provides methods for preparing compounds of the invention.

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