1375468-12-4Relevant articles and documents
Coupling the near-infrared fluorescent dye IR-780 with cabazitaxel makes renal cell carcinoma chemotherapy possible
Zheng, Yu,Lan, Ting,Wei, Di,Zhang, Geng,Hou, Guangdong,Yuan, Jiarui,Yan, Fei,Wang, Fuli,Meng, Ping,Yang, Xiaojian,Chen, Guo,Zhu, Zheng,Lu, Zifan,He, Wei,Yuan, Jianlin
, (2019)
Renal cell carcinoma (RCC) has always been considered resistant to chemotherapy. IR-780 is a near-infrared fluorescent (NIRF) dye that can be efficiently taken up by RCC cells. Cabazitaxel is a cytotoxic drug that interferes with mitosis by acting on tubu
Polymeric conjugates of active principles, their process of preparation and their polymeric intermediates
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Page/Page column 17-18, (2016/06/01)
The present invention relates to novel conjugates of active principles grafted to a polymer, to the nanoparticles comprising them, to their preparation and to their polymeric intermediates.
Targeted Conjugates Encapsulated in Particles and Formulations Thereof
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Paragraph 0270; 0271, (2014/07/08)
Particles, including nanoparticles and microparticles, and pharmaceutical formulations thereof, containing conjugates of an active agent such as a therapeutic, prophylactic, or diagnostic agent attached to a targeting moiety via a linker have been designed which can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer or infectious diseases.