137601-32-2

Basic information

• Product Name: (2Z)-2-methyl-2-butenoic 2,4,6-trichlorobenzoic anhydride
• Synonyms: (2Z)-2-methyl-2-butenoic 2,4,6-trichlorobenzoic anhydride
• CAS NO: 137601-32-2
• Molecular Weight: 307.561
• Mol File: 137601-32-2.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: (2Z)-2-methyl-2-butenoic 2,4,6-trichlorobenzoic anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z)-2-methyl-2-butenoic 2,4,6-trichlorobenzoic anhydride(137601-32-2)
• EPA Substance Registry System: (2Z)-2-methyl-2-butenoic 2,4,6-trichlorobenzoic anhydride(137601-32-2)

Safety Data

• Hazardous Substances Data: 137601-32-2(Hazardous Substances Data)

Usage

General Description

(2Z)-2-methyl-2-butenoic 2,4,6-trichlorobenzoic anhydride is a chemical compound consisting of a 2-methyl-2-butenoic acid combined with 2,4,6-trichlorobenzoic anhydride. The 2-methyl-2-butenoic acid, also known as tiglic acid, is a colorless liquid with a pungent odor, commonly used as a flavoring and fragrance agent. 2,4,6-trichlorobenzoic anhydride is a highly reactive chemical compound used in the synthesis of various organic compounds. When combined, these two chemicals form a complex compound with potentially unique properties and applications in various industries such as pharmaceuticals, chemical synthesis, and agriculture. Additionally, the resulting compound may exhibit specific chemical reactivity and behavior due to the presence of the tiglic acid and trichlorobenzoic anhydride components.

Upstream product

• 565-63-9 Angelic acid 
• 4136-95-2 2,4,6-trichlorobenzoyl chloride 

Downstream Products

• 84254-87-5 (Z)-<(E)-3-Phenyl-2-propenyl> 2-Methyl-2-butenoate 
• 18456-00-3 (-)-Bakkenolide C 
• 137601-37-7 (Z)-(1-Methylcyclohexyl) 2-Methyl-2-butenoate 
• 136051-63-3 nortrilobolide 
• 123269-03-4 thiapsigargin 
• 1356187-27-3 ingenol-3-tigliate 
• 75567-37-2 ingenol mebutate 
• 87980-68-5 3-O-angeloyl-5,20-O-isopropylideneingenol 
• 26577-85-5 Petasin 
• 18455-98-6 bakkenolide B 
• 73777-65-8 (5,8-dihydro-7-methoxy-6-methyl-5,8-dioxo-1-isoquinolinyl)methyl (2Z)-2-methyl-2-butenoate 
• 50657-07-3 trilobolide 
• 828915-98-6 (Z)-2-Methyl-but-2-enoic acid (3aR,4S,7aR)-3-methylene-5-((S)-1-methyl-4-trityloxy-butyl)-2-oxo-6-trityloxymethyl-2,3,3a,4,7,7a-hexahydro-benzofuran-4-yl ester 
• 690254-83-2 (5-benzyloxy-7-methoxy-6-methylisoquinol-1-yl)methyl angelate 

Relevant articles and documents

Studies on the stereostructure of eudesmanolides from Umbelliferae: Total synthesis of (+)-decipienin A

The first total synthesis of (+)-decipienin A has been achieved in 4% overall yield in seven steps from (+)-dihydrocarvone, thus confirming the stereostructure proposed by Holub et al. (Holub, M.; Budesinsky, M. Phytochemistry 1986, 25, 2015-2026) for thi

Enantioselective synthesis of (+)-decipienin A

The enantioselective synthesis of (+)-decipienin A has been carried out. The oxidation of 7-epi-cyperone 2 with molecular oxygen in the presence of methanolic KOH provides de C-6-hydroxylated derivative in quantitative yield. The oxidation of glycols 5a t

Semisynthesis of (+)-angeloyl-gutierrezianolic acid methyl ester diterpenoid

This paper describes the use of zamoranic acid in the first semisynthesis of the furolabdane (+)-angeloyl-gutierrezianolic acid methyl ester diterpenoid, which also establishes the absolute configuration of the natural product. Direct deconjugation of Δs

Semisynthesis of ingenol 3-angelate (PEP005): Efficient stereoconservative angeloylation of alcohols

A high-yielding method was developed for the preparation of ingenol 3-angelate (PEP005, ingenol mebutate) via the corresponding 5,20-acetonide without concomitant isomerization of the angelate (Z-form) to the corresponding tiglate (E-form). The general sc

Synthesis and cytotoxic evaluation of some cribrostatin-ecteinascidin analogues

Analogues of cribrostatin IV (1) and the potent antineoplastic agent ecteinascidin 743 (2) have been synthesized. The cytotoxic activity of these compounds (5, 14, 20) has been determined, and the cyanoamine-cribrostatin analogue (14) exhibits a 20-fold improvement with regard to the natural product 1.