1378021-29-4

Basic information

• Product Name: 2-(4-fluorophenyl)-3,5,6,7-tetrahydro-2-(2-thienyl)benzofuran-4(2H)-one
• CAS NO: 1378021-29-4
• Molecular Weight: 314.38
• Mol File: 1378021-29-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-fluorophenyl)-3,5,6,7-tetrahydro-2-(2-thienyl)benzofuran-4(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-fluorophenyl)-3,5,6,7-tetrahydro-2-(2-thienyl)benzofuran-4(2H)-one(1378021-29-4)
• EPA Substance Registry System: 2-(4-fluorophenyl)-3,5,6,7-tetrahydro-2-(2-thienyl)benzofuran-4(2H)-one(1378021-29-4)

Safety Data

• Hazardous Substances Data: 1378021-29-4(Hazardous Substances Data)

Upstream product

• 1343477-51-9 2-[1-(4-fluorophenyl)ethenyl]thiophene 
• 504-02-9 1,3-cylohexanedione 

Relevant articles and documents

Radical cyclization reactions via manganese(III) acetate leading to 2-thienyl-substituted dihydrofuran compounds

The 2-thienyl-substituted 4,5-dihydrofuran derivatives 3-8 were obtained by the radical cyclization reaction of 1,3-dicarbonyl compounds 1a-1f with 2-thienyl-substituted conjugated alkenes 2a-2e by using [Mn(OAc)3] (Tables 1-5). In this study, reactions of 1,3-dicarbonyl compounds 1a-1e with alkenes 2a-2c gave 4,5-dihydrofuran derivatives 3-5 in high yields (Tables 1-3). Also the cyclic alkenes 2d and 2e gave the dihydrobenzofuran compounds, i.e., 6 and 7 in good yields (Table 4). Interestingly, the reaction of benzoylacetone (=1-phenylbutane-1,3-dione; 1f) with some alkenes gave two products due to generation of two stable carbocation intermediates (Table 5). Copyright