1378239-14-5Relevant articles and documents
BENZOCYCLOOCTENE-BASED AND INDENE-BASED ANTICANCER AGENTS
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, (2018/02/27)
Benzocyclooctene (fused 6,8 ring system) analogues and corresponding indene (fused 6,5 ring system) analogues function as inhibitors of tubulin polymerization. The compounds are useful as anticancer agents in a new therapeutic approach for cancer treatment utilizing small-molecule inhibitors of tubulin polymerization that also act as vascular disrupting agents (VDAs).