1379148-15-8

Basic information

• Product Name: diethyl 7-oxo-7H-benzo[de]indolo[2,1-a]isoquinolin-13-ylphosphate
• Synonyms: diethyl 7-oxo-7H-benzo[de]indolo[2,1-a]isoquinolin-13-ylphosphate
• CAS NO: 1379148-15-8
• Molecular Weight: 421.389
• Mol File: 1379148-15-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl 7-oxo-7H-benzo[de]indolo[2,1-a]isoquinolin-13-ylphosphate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 7-oxo-7H-benzo[de]indolo[2,1-a]isoquinolin-13-ylphosphate(1379148-15-8)
• EPA Substance Registry System: diethyl 7-oxo-7H-benzo[de]indolo[2,1-a]isoquinolin-13-ylphosphate(1379148-15-8)

Safety Data

• Hazardous Substances Data: 1379148-15-8(Hazardous Substances Data)

Upstream product

• 1379148-12-5 diethyl {2-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)}benzoylphosphonate 
• 122-52-1 triethyl phosphite 
• 81-84-5 1,8-Naphthalic anhydride 
• 56813-57-1 N,N-(1,8-naphthaloyl)-2-aminobenzoyl chloride 

Relevant articles and documents

A novel approach to isoindolo[2,1-a]indol-6-ones

A convenient route to isoindolo[2,1-a]indol-6-ones has been developed starting from the appropriate 2-(N-phthaloyl)benzoic acids. Formation of the acid chlorides with thionyl chloride followed by heating with triethyl phosphite in a suitable solvent resulted in a multistep reaction giving tetracyclic β-ketophosphonates that on reduction with sodium borohydride gave the required indolones in good overall yields. Analogous β-ketophosphonates were also prepared starting with N,N-(1,8-naphthaloyl)-2-aminobenzoic acid and 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acids although of these only the naphthaloyl product could be reduced with sodium borohydride without cleaving the amide bond in the ring system.