1379772-23-2

Basic information

• Product Name: C₁₈H₁₈O₅
• CAS NO: 1379772-23-2
• Molecular Weight: 314.338
• Mol File: 1379772-23-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₈O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₈O₅(1379772-23-2)
• EPA Substance Registry System: C₁₈H₁₈O₅(1379772-23-2)

Safety Data

• Hazardous Substances Data: 1379772-23-2(Hazardous Substances Data)

Upstream product

• 2406-23-7 (R)-ethyl 2-hydroxy-2-phenylpropanoate 
• 1885-14-9 phenyl chloroformate 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 1603-79-8 phenylglyoxylic acid ethyl ester 

Downstream Products

• 1379772-21-0 (R)-5-methyl-5-phenyl-3-(phenylamino)oxazolidine-2,4-dione 

Relevant articles and documents

Highly homogeneous stereocontrolled construction of quaternary hydroxyesters by addition of dimethylzinc to α-ketoesters promoted by chiral perhydrobenzoxazines and B(OEt)3

A highly efficient enantioselective addition of Me2Zn to α-ketoesters, assisted by a chiral perhydro-1,3-benzoxazine ligand, is described. This novel catalytic system offers homogeneous elevated enantioselectivities in the preparation of α-hydroxyesters that bear a quaternary stereocenter, with a minor dependence on electronic and steric effects when aromatic, heteroaromatic, or aliphatic α-ketoesters are employed. The catalyst can be recovered and reused without loss of activity.