1380434-33-2

Basic information

• Product Name: 2-ethyl-7-(2-methoxy-4-methylphenyl)-3-nitropyrazolo[1,5-a]pyridine
• Synonyms: 2-ethyl-7-(2-methoxy-4-methylphenyl)-3-nitropyrazolo[1,5-a]pyridine
• CAS NO: 1380434-33-2
• Molecular Weight: 311.34
• Mol File: 1380434-33-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-ethyl-7-(2-methoxy-4-methylphenyl)-3-nitropyrazolo[1,5-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethyl-7-(2-methoxy-4-methylphenyl)-3-nitropyrazolo[1,5-a]pyridine(1380434-33-2)
• EPA Substance Registry System: 2-ethyl-7-(2-methoxy-4-methylphenyl)-3-nitropyrazolo[1,5-a]pyridine(1380434-33-2)

Safety Data

• Hazardous Substances Data: 1380434-33-2(Hazardous Substances Data)

Upstream product

• 475174-68-6 7-bromo-2-ethylpyrazolo[1,5-a]pyridine 
• 475174-64-2 1-(but-1-yn-1-yl)pyridine 
• 475174-67-5 N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate 
• 475174-71-1 7-bromo-2-ethyl-3-nitropyrazolo[1,5-a]pyridine 
• 198211-79-9 (2-methoxy-4-methylphenyl)boronic acid 
• 475174-65-3 2-ethylpyrazolo[1,5-a]pyridine 
• 109-04-6 2-bromo-pyridine 

Relevant articles and documents

Synthesis and structure-activity relationships of pyrazolo[1,5-a]pyridine derivatives: Potent and orally active antagonists of corticotropin-releasing factor 1 receptor

Design, synthesis, and structure-activity relationships of a series of 3-dialkylamino-7-phenyl pyrazolo[1,5-a]pyridines (I) as selective antagonists of the corticotropin-releasing factor 1 (CRF1) receptor are described. The most prominent compound to emerge from this work, 46 (E2508), exhibits potent in vitro activity, excellent drug-like properties, and robust oral efficacy in animal models of stress-related disorders. It has advanced into clinical trials.