138154-61-7Relevant articles and documents
Synthetic use of the primary kinetic isotope effect in hydrogen atom transfer: Generation of α-aminoalkyl radicals
Wood, Mark E.,Bissiriou, Sabine,Lowe, Christopher,Norrish, Andrew M.,Senechal, Katell,Windeatt, Kim M.,Coles, Simon J.,Hursthouse, Michael B.
experimental part, p. 4653 - 4665 (2010/11/17)
The extent to which deuterium can act as a protecting group to prevent unwanted 1,5-hydrogen atom transfer to aryl and vinyl radical intermediates was examined in the context of the generation of α-aminoalkyl radicals in a pyrrolidine ring. Intra- and int
An approach to α-substituted amines
Williams, Lorenzo,Booth, Susan E.,Undheim, Kjell
, p. 13697 - 13708 (2007/10/02)
A number of amines have been alkylated at the position alpha to nitrogen via free radical methodology. N-(2-iodobenzyl) and N-(2-iodobenzoyl) 'protected' amines have been used to generate radicals which rapidly undergo a 1,5-hydrogen shift to give more st
Generation and Alkylation of Carbanions α to the Nitrogen of Amines by a New Metalation Procedure
Murakami, Masahiro,Hayashi, Minoru,Ito, Yoshihiko
, p. 793 - 794 (2007/10/02)
Treatment of a tertiary amine having a pendent o-iodobenzyl group on nitrogen with SmI2 generates α-amino organosamarium, which reacts with electrophiles giving the corresponding C-C bond formation products in good yield.