13831-03-3 Usage
Description
TERT-BUTYL PROPIOLATE, also known as tert-butyl propionate, is an organic ester compound derived from propionic acid and tert-butyl alcohol. It is a colorless liquid with a distinctive odor and is known for its reactivity in various chemical reactions, making it a versatile building block in organic synthesis.
Uses
Used in Pharmaceutical Industry:
TERT-BUTYL PROPIOLATE is used as a synthetic intermediate for the preparation of heterocycles, alkaloids, and unsaturated amino acids, which are essential components in the development of various pharmaceutical compounds. Its ability to participate in a wide range of reactions allows for the creation of diverse drug candidates with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, TERT-BUTYL PROPIOLATE serves as a valuable reagent for the preparation of various organic compounds. Its reactivity with different substrates enables the synthesis of complex molecules, which can be further utilized in the development of new materials, dyes, and other specialty chemicals.
Used in Research and Development:
TERT-BUTYL PROPIOLATE is also used in research and development laboratories for the study of its chemical properties and potential applications. Crystallographic data for the lithium enolate of TERT-BUTYL PROPIOLATE has been described, which contributes to the understanding of its structure and reactivity. This knowledge can be applied to optimize synthetic routes and develop new methodologies in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 13831-03-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,8,3 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13831-03:
(7*1)+(6*3)+(5*8)+(4*3)+(3*1)+(2*0)+(1*3)=83
83 % 10 = 3
So 13831-03-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H10O2/c1-5-6(8)9-7(2,3)4/h1H,2-4H3
13831-03-3Relevant articles and documents
Palladium-Catalyzed Regio- and Stereoselective Coupling-Addition of Propiolates with Arylsulfonyl Hydrazides: A Pattern for Difunctionalization of Alkynes
Liu, Lixin,Sun, Kang,Su, Lebin,Dong, Jianyu,Cheng, Lei,Zhu, Xiaodong,Au, Chak-Tong,Zhou, Yongbo,Yin, Shuang-Feng
supporting information, p. 4023 - 4027 (2018/07/15)
A new pattern for difunctionalization of alkynes via a palladium-catalyzed regio- and stereoselective coupling-addition of propiolates with arylsulfonyl hydrazides is disclosed. The approach enables the synthesis of various highly functionalized (E)-vinylsulfones in satisfactory yields. Arylsulfonyl hydrazides act as both aryl and sulfonyl sources via selective cleavage of Ar(C)-S and S-N bonds, which are simultaneously incorporated onto the terminal carbon atom of an alkyne molecule.
Gold-catalyzed formal [4π+2π]-cycloadditions of tert-butyl propiolates with aldehydes and ketones to form 4H-1,3-dioxine derivatives
Karad, Somnath Narayan,Chung, Wei-Kang,Liu, Rai-Shung
supporting information, p. 13004 - 13007 (2015/08/06)
Gold-catalyzed formal hetero-[4π+2π] cycloadditions of tert-butyl propiolates with carbonyl compounds proceeded efficiently to yield 4H-1,3-dioxine derivatives over a wide scope of substrates. With acetone as a promoter, gold-catalyzed cycloadditions of these propiolate derivatives with enol ethers led to the formation of atypical [4+2]-cycloadducts with skeletal rearrangement.
Preparation of 3-bromopropiolic esters:methyl and tert-butyl 3-bromopropiolates
Leroy
, p. 212 - 212 (2017/09/08)
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