138387-16-3 Usage
Description
CIS,TRANS-DOXEPIN-D3, also known as 3-Dibenz[b,e]oxepin-11(6H)-ylidene-N-methyl-N-(methyl-d3)-1-propanamine, is a deuterium analog of doxepin synthesized by the N-Doxepin carbamate with lithium aluminum deuteride. It is a compound with potential applications in various fields due to its unique properties.
Uses
Used in Pharmaceutical Industry:
CIS,TRANS-DOXEPIN-D3 is used as an intermediate in the synthesis of Doxepin-d3 Hydrochloride (D550002), which is a labeled version of Doxepin (D550000). Doxepin is a clinically used anti-depressant that helps in treating anxiety and depression. The deuterium-labeled version, Doxepin-d3, can be utilized for research purposes, such as studying the metabolism, pharmacokinetics, and potential drug interactions of doxepin in the body.
Used in Research and Development:
CIS,TRANS-DOXEPIN-D3 can be employed as a research tool in the development of new drugs and therapies. Its deuterium-labeled nature allows for the investigation of the effects of isotopic substitution on the compound's properties, such as stability, solubility, and binding affinity to target proteins. This information can be valuable in the design of more effective and safer medications for various conditions, including anxiety and depression.
Used in Analytical Chemistry:
CIS,TRANS-DOXEPIN-D3 can be utilized as a labeled internal standard in analytical chemistry for the quantification of doxepin and its metabolites in biological samples. The use of a deuterium-labeled internal standard can improve the accuracy and precision of measurements, as it helps to account for variations in sample preparation, extraction, and instrumental analysis.
Check Digit Verification of cas no
The CAS Registry Mumber 138387-16-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,3,8 and 7 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 138387-16:
(8*1)+(7*3)+(6*8)+(5*3)+(4*8)+(3*7)+(2*1)+(1*6)=153
153 % 10 = 3
So 138387-16-3 is a valid CAS Registry Number.
