138423-98-0

Basic information

• Product Name: N-Acetic acid-indole-3-carboxaldehyde
• Synonyms: 2-(3-methanoylindol-1-yl)ethanoic acid;3-FORMYLINDOLE-1-ACETIC ACID;(3-Formyl-1-indolyl)acetic acid≥ 97% (HPLC);1-(Carboxymethyl)indole-3-carboxaldehyde;TIMTEC-BB SBB010076;N-ACETIC ACID-INDOLE-3-CARBOXALDEHYDE;(3-FORMYL-1-INDOLYL)ACETIC ACID;3-FORMYL INDOLEACETIC ACID
• CAS NO: 138423-98-0
• Molecular Formula: C₁₁H₉NO₃
• Molecular Weight: 203.19
• Product Categories: Indoles and derivatives;Aromatic Aldehydes & Derivatives (substituted);Heterocyclic Compounds;Indoles;Bifunctional CrosslinkersBuilding Blocks;Heterocyclic Building Blocks;Linkers;Peptide Synthesis
• Mol File: 138423-98-0.mol
• Article Data: 13

Chemical Properties

• Melting Point: 197-200 °C(lit.)
• Boiling Point: 458.5 °C at 760 mmHg
• Flash Point: 231.1 °C
• Appearance: /
• Density: 1.3 g/cm³
• Vapor Pressure: 3.34E-09mmHg at 25°C
• Refractive Index: 1.621
• Storage Temp.: 2-8°C
• PKA: 4.15±0.10(Predicted)
• Sensitive: Air Sensitive
• BRN: 5431204
• CAS DataBase Reference: N-Acetic acid-indole-3-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: N-Acetic acid-indole-3-carboxaldehyde(138423-98-0)
• EPA Substance Registry System: N-Acetic acid-indole-3-carboxaldehyde(138423-98-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 8-10-23
• HazardClass: IRRITANT
• Hazardous Substances Data: 138423-98-0(Hazardous Substances Data)

Usage

Chemical Properties

Solid

Uses

Handle to synthesize an indolecarboxaldehyde resin by coupling to an amino-resin. Amines and derivatives can be immobilized by reductive amination of this aldehyde resin. Mild cleavage with 50% TFA

InChI:InChI=1/C11H9NO3/c13-7-8-5-12(6-11(14)15)10-4-2-1-3-9(8)10/h1-5,7H,6H2,(H,14,15)

Upstream product

• 487-89-8 Indole-3-carboxaldehyde 
• 7748-25-6 potassium chloroacetate 
• 27065-94-7 (3-formylindol-1-yl)acetic acid ethyl ester 
• 120-72-9 indole 
• 363590-49-2 2-(3-formyl-1H-indol-1-yl)acetic acid tert-butyl ester 

Downstream Products

• 588-46-5 N-(phenylmethyl)acetamide 
• 335207-46-0 1-[2-(4-morpholinyl)-2-oxoethyl]-1H-indole-3-carboxaldehyde 
• 138423-99-1 3-hydroxymethyl-N-carboxymethylindole 

Relevant articles and documents

AMIDES OF ANTHRACYCLINE ANTIBIOTICS AND N-CARBOXYMETHYLASCORBIGEN

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New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: Discovery, characterization, and crystal structure in complex with the target

Terminal deoxynucletidyl transferase (TdT) is overexpressed in some cancer types, where it might compete with pol μ during the mutagenic repair of double strand breaks (DSBs) through the nonhomologous end joining (NHEJ) pathway. Here we report the discove

PHAMACEUTICAL PREPARATIONS COMPRISING INSULIN

Novel preparations comprising ligands for the HisB10 Zn2+ sites of the R-state insulin hexamer wherein the ligand is extended by protamine that are capable of prolonging the ac-tion of insulin preparations.