1384259-02-2

Basic information

• Product Name: C₃₆H₄₇N₃O₄
• CAS NO: 1384259-02-2
• Molecular Weight: 585.787
• Mol File: 1384259-02-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₃₆H₄₇N₃O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₆H₄₇N₃O₄(1384259-02-2)
• EPA Substance Registry System: C₃₆H₄₇N₃O₄(1384259-02-2)

Safety Data

• Hazardous Substances Data: 1384259-02-2(Hazardous Substances Data)

Upstream product

• 139962-95-1 2-formyl-4-methoxyphenylboronic acid 
• 879498-90-5 1H-indole-6-carboxylic acid, 2-bromo-3-cyclohexyl-, 1,1-dimethylethyl ester 
• 1204417-91-3 tert-butyl 3-cyclohexyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-6-carboxylate 
• 928844-30-8 13-cyclohexyl-3-methoxy-7H-indolo[2,1-a][2]benzazepine-6,10-dicarboxylic acid 10-(1,1-dimethylethyl) ester 6-methyl ester 
• 16011-97-5 N,N'-dimethyl-1,4-butanediamine 
• 1038924-00-3 7H-indolo[2,1-a][2]benzazepine-6,10-dicarboxylic acid, 13-cyclohexyl-3-methoxy-, 10-(1,1-dimethylethyl) ester 

Downstream Products

• 1384259-10-2 C₃₆H₄₈N₄O₆S 
• 1384259-18-0 C₃₂H₄₀N₄O₆S 
• 1204417-13-9 11H-2,18-methano-3,7:4,1-dimetheno-10,2,9,11,16-benzothiatetraazacycloheneicosine-8,17(9H,12H)-dione, 26-cyclohexyl-13,14,15,16-tetrahydro-21-methoxy-11,16-dimethyl-, 10,10-dioxide 

Relevant articles and documents

Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties

The concept of drug-likeness distills the physicochemical properties of small-molecule drugs to a set of rules. Macrocyclic drugs are known to break these rules. A structure-based macrocyclization strategy was applied to design new hepatitis C virus NS5B inhibitors with improved pharmacokinetic properties, exemplifying a rational strategy for overcoming the confines of standard drug-like chemical space . Copyright